Escherichia coli strain H17

Escherichia coli strain H17 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, capable of thriving in both aerobic and anaerobic environments. It is characterized by its mobility, facilitated by the presence of flagella, and typically exists in pairs or as single cells. Optimally, this strain grows at 37°C, placing it within the mesophilic temperature range. H17 is free-living and has a diverse range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. This wide host range underlines its ecological versatility, suggesting an ability to adapt to different biological environments. The strain is associated with numerous health effects, particularly in humans, where it can cause urinary tract infections, gastrointestinal infections, and even severe conditions such as septicemia and hemolytic uremic syndrome (HUS). Its pathogenicity highlights its role as a significant human pathogen, capable of leading to both mild and severe disease outcomes, including neonatal meningitis and acute bacterial meningitis. The presence of six replicons and two membranes indicates a complex genomic structure that may contribute to its adaptability and pathogenic potential. The health implications of E. coli strain H17 reinforce its ecological significance, particularly in understanding the dynamics of host-microbe interactions and the potential for zoonotic transmission.