Escherichia coli strain 103

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 103 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in various oxygen conditions. This strain is motile, possessing flagella, and typically arranges itself in pairs and singles. Its optimal growth temperature is 37°C, classifying it as mesophilic. E. coli strain 103 is primarily host-associated, with a diverse range of hosts including humans (Homo sapiens), various mammals (e.g., Bos taurus, Sus scrofa), birds (Aves), amphibians, and even certain plants like Solanum lycopersicum and Brassica oleracea var. italica. This broad host range indicates its adaptability and ecological versatility. The strain is known for its pathogenic potential, linked to numerous health issues such as urinary tract infections (UTIs), gastrointestinal infections, and severe conditions like hemolytic uremic syndrome (HUS) and septicemia. These health effects underscore the strain's role in both human and veterinary medicine, highlighting its impact on public health and agriculture. E. coli strain 103 possesses two replicons and two membranes, suggesting complex genomic organization typical of many Enterobacteriaceae. Its ability to cause a variety of diseases, from diarrhea to neonatal meningitis, indicates a significant ecological role, as it can inhabit and affect multiple species, thereby influencing both host health and microbial community dynamics. This adaptability underscores the importance of monitoring and understanding such pathogens in ecological and clinical contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 103

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 103
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 103


Gene Summary

Adenine Count

29595 bp

Thymine Count

30048 bp

Guanine Count

29952 bp

Cytosine Count

31073 bp

Genome Length

120668 bp

Protein-coding Genes

121 genes

Non-Coding Genes

26 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive41779 - 41791Not Available
Restriction endonuclease subunit sCPA47_RS25755Not AvailableNegative45933 - 4720448202.5
Putative restriction-modification proteinCPA47_RS25760Not AvailableNegative47201 - 4875757764.1
Prevention of host death by doc toxicityCPA47_RS25765Not AvailablePositive48940 - 491618133.53
Toxin docCPA47_RS25770Not AvailablePositive49161 - 4954113616.1
PdcaCPA47_RS25775Not AvailablePositive49546 - 497256748.57
Conserved protein of unknown function pdcbCPA47_RS25780Not AvailablePositive49753 - 5003110600.9
Putative transposase orfbCPA47_RS25785Not AvailablePositive50036 - 5044915974.7
Putative replication protein repaCPA47_RS25795Not AvailablePositive51245 - 5222237286.0
Putative recombinase xerdCPA47_RS25800Not AvailableNegative52507 - 5324728193.5

Displaying genes 1 – 10 of 217 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 74 in total