Streptococcus salivarius strain FDAARGOS_259

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus salivarius strain FDAARGOS_259 is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. As a facultative anaerobe, it thrives in environments with or without oxygen, making it versatile in its habitat. This strain is host-associated, primarily found in Homo sapiens, where it engages in a free-living biotic relationship. One notable aspect of S. salivarius FDAARGOS_259 is its pathogenic potential, as it has been linked to various health issues in humans, including bacteremia, pneumonia, endocarditis, peritonitis, and meningitis. These associations underscore the strain's significance in clinical microbiology and its relevance in understanding human health. The strain has a mesophilic temperature range, indicating it is optimized for growth at moderate temperatures typical of the human body. It is non-motile, lacking flagella, which suggests that it relies on other mechanisms for colonization and interaction with host tissues. With only one replicon, S. salivarius FDAARGOS_259's genome structure may allow for streamlined genetic regulation, potentially influencing its adaptability and virulence. Understanding the traits of this strain contributes to broader insights into the ecological roles of Streptococcus species in human health, particularly regarding their dual nature as commensals and potential pathogens. This duality highlights the importance of continuous monitoring and study of such strains to better inform clinical practices and public health strategies.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus salivarius
Strainstrain FDAARGOS_259

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus salivarius strain FDAARGOS_259
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus salivarius strain FDAARGOS_259 chromosome, complete

Gene Summary

Adenine Count

677315 bp

Thymine Count

675212 bp

Guanine Count

452009 bp

Cytosine Count

454782 bp

Genome Length

2259318 bp

Protein-coding Genes

1966 genes

Non-Coding Genes

188 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
amino acid abc transporter permeaseA6J87_RS10335Not AvailablePositive2141834 - 214248724317.9
cell surface ecto-5'-nucleotidase nt5eA6J87_RS10340Not AvailablePositive2142598 - 214484479304.0
arac family transcriptional regulatorA6J87_RS10345Not AvailableNegative2144880 - 214582137484.6
trna uridine-5-carboxymethylaminomethyl(34) synthesis gtpase mnmeA6J87_RS10350Not AvailableNegative2145965 - 214733550330.4
alanine/glycine:cation symporter family proteinA6J87_RS10355Not AvailableNegative2147462 - 214880547827.3
dna helicase pcraA6J87_RS10360Not AvailablePositive2149315 - 215162487046.5
o-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family proteinA6J87_RS10365Not AvailablePositive2151745 - 215302546248.9
had hydrolase family proteinA6J87_RS10370Not AvailablePositive2153086 - 215384128536.4
thiol peroxidaseA6J87_RS10375Not AvailablePositive2153906 - 215440018148.4
restriction endonuclease subunit sA6J87_RS10380Not AvailablePositive2154527 - 215514723440.1

Displaying genes 2061 – 2070 of 2154 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC11536889
BacteremiaCausesPMC11536889
EndocarditisCausesPMC11536889
MeningitisCausesPMC11536889
PeritonitisCausesPMC9615012

Displaying health effects 1 – 5 of 5 in total