Klebsiella pneumoniae subsp. pneumoniae strain RJA166

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain RJA166 is a Gram-negative, rod-shaped bacterium recognized as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is categorized as a chemoheterotroph, indicating it derives energy from organic compounds. It is typically found in host-associated habitats and exhibits mobility due to the presence of flagella. The cells of K. pneumoniae RJA166 can be observed in various arrangements, including chains, pairs, and singles. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, suggesting its adaptation to a host environment. The bacterium has a complex cellular structure comprising two membranes and four replicons, which may play a role in its genetic stability and adaptability. Klebsiella pneumoniae is notably associated with health impacts, including pneumonia and community-acquired pneumonia (CAP), posing a significant risk in clinical settings. Its ability to exist as a free-living organism further complicates its management, as it can persist in various environments. Understanding the traits of K. pneumoniae RJA166 provides insight into its ecological role and potential pathogenicity. The bacterium's adaptability to host-associated environments, coupled with its mobility and energy acquisition strategies, highlights its opportunistic nature and the challenges it poses in healthcare contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain RJA166

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain RJA166
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain RJA166 chromosome,

Gene Summary

Adenine Count

1134101 bp

Thymine Count

1134159 bp

Guanine Count

1538728 bp

Cytosine Count

1541380 bp

Genome Length

5348368 bp

Protein-coding Genes

4957 genes

Non-Coding Genes

231 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
formate hydrogenlyase transcriptional activator flhaRJA_RS05330Not AvailableNegative1060240 - 106231278235.4
hydrogenase expression/formation protein hypeRJA_RS05335Not AvailableNegative1062549 - 106355934817.0
hydrogenase formation protein hypdRJA_RS05340Not AvailableNegative1063556 - 106467741259.6
hypc/hybg/hupf family hydrogenase formation chaperoneRJA_RS05345Not AvailableNegative1064677 - 10649499713.72
hydrogenase nickel incorporation protein hypbRJA_RS05350Not AvailableNegative1064940 - 106581231553.8
hydrogenase maturation nickel metallochaperone hypaRJA_RS05355Not AvailableNegative1065816 - 106616012924.5
formate hydrogenlyase regulator hycaRJA_RS05360Not AvailablePositive1066370 - 106681917116.2
4fe-4s dicluster domain-containing proteinRJA_RS05370Not AvailablePositive1066902 - 106751021834.3
formate hydrogenlyase subunit 3RJA_RS05375Not AvailablePositive1067507 - 106933364006.1
respiratory chain complex i subunit 1 family proteinRJA_RS05380Not AvailablePositive1069336 - 107025932958.4

Displaying genes 1181 – 1190 of 5811 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total