Bacteroides fragilis strain Q1F2

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain Q1F2 is a Gram-negative, rod-shaped, anaerobic bacterium that thrives in host-associated environments. It is a chemoorganotroph, indicating that it derives energy from organic compounds, and it exists as single cells rather than in clusters or chains. This strain has three replicons and possesses two membranes, characteristic of its Gram-negative classification. With an optimal growth temperature of 37°C, Bacteroides fragilis strain Q1F2 is classified as mesophilic, showing preference for moderate temperature ranges. Although it is non-motile, the presence of flagella may play a role in its interactions within the host environment. Bacteroides fragilis strain Q1F2 is free-living and has been identified in various hosts, including Homo sapiens (humans), Gallus gallus (chickens), various Metazoa (multicellular organisms), Equidae (horses), and Serpentes (snakes). Its pathogenic potential in humans is significant; it is associated with conditions such as bacteremia, abscesses, colitis, and colorectal cancer, among others. The strain's relationship with its hosts emphasizes its dual role as a commensal organism and a pathogen. While it contributes to the normal gut microbiota, it can also lead to serious health complications, particularly when it breaches host barriers. This duality highlights the complexity of microbial interactions within host ecosystems and the potential consequences of dysbiosis.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain Q1F2

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain Q1F2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain Q1F2 plasmid Q1F2-p1, complete

Gene Summary

Adenine Count

13723 bp

Thymine Count

12938 bp

Guanine Count

8990 bp

Cytosine Count

9699 bp

Genome Length

45350 bp

Protein-coding Genes

29 genes

Non-Coding Genes

2 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cell division protein ftsq/divibBUN20_RS20745Not AvailableNegative4756034 - 475677428072.9
udp-n-acetylmuramate--l-alanine ligaseBUN20_RS20750Not AvailableNegative4756806 - 475820051782.9
undecaprenyldiphospho-muramoylpentapeptide beta-n-acetylglucosaminyltransferaseBUN20_RS20755Not AvailableNegative4758197 - 475933941198.5
ftsw/roda/spove family cell cycle proteinBUN20_RS20760Not AvailableNegative4759341 - 476063647177.9
acyltransferaseBUN20_RS20765Not AvailableNegative4760695 - 476202849465.6
phospho-n-acetylmuramoyl-pentapeptide- transferaseBUN20_RS20770Not AvailableNegative4762169 - 476343746871.6
udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2, 6-diaminopimelate ligaseBUN20_RS20775Not AvailableNegative4763522 - 476497953370.1
penicillin-binding proteinBUN20_RS20780Not AvailableNegative4764997 - 476709676926.7
ftsl-like putative cell division proteinBUN20_RS20785Not AvailableNegative4767124 - 476746513272.1
16s rrna (cytosine(1402)-n(4))-methyltransferase rsmhBUN20_RS20790Not AvailableNegative4767494 - 476840834636.4

Displaying genes 3981 – 3990 of 4436 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total