Bacteroides fragilis strain Q1F2

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis strain Q1F2 is a Gram-negative, rod-shaped, anaerobic bacterium that thrives in host-associated environments. It is a chemoorganotroph, indicating that it derives energy from organic compounds, and it exists as single cells rather than in clusters or chains. This strain has three replicons and possesses two membranes, characteristic of its Gram-negative classification. With an optimal growth temperature of 37°C, Bacteroides fragilis strain Q1F2 is classified as mesophilic, showing preference for moderate temperature ranges. Although it is non-motile, the presence of flagella may play a role in its interactions within the host environment. Bacteroides fragilis strain Q1F2 is free-living and has been identified in various hosts, including Homo sapiens (humans), Gallus gallus (chickens), various Metazoa (multicellular organisms), Equidae (horses), and Serpentes (snakes). Its pathogenic potential in humans is significant; it is associated with conditions such as bacteremia, abscesses, colitis, and colorectal cancer, among others. The strain's relationship with its hosts emphasizes its dual role as a commensal organism and a pathogen. While it contributes to the normal gut microbiota, it can also lead to serious health complications, particularly when it breaches host barriers. This duality highlights the complexity of microbial interactions within host ecosystems and the potential consequences of dysbiosis.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
Strainstrain Q1F2

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis strain Q1F2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain Q1F2 plasmid Q1F2-p1, complete

Gene Summary

Adenine Count

13723 bp

Thymine Count

12938 bp

Guanine Count

8990 bp

Cytosine Count

9699 bp

Genome Length

45350 bp

Protein-coding Genes

29 genes

Non-Coding Genes

2 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf4248 domain-containing proteinBUN20_RS11150Not AvailablePositive2550625 - 255093612092.5
hypothetical proteinBUN20_RS11160Not AvailablePositive2551445 - 255206524215.0
ferritinBUN20_RS11165Not AvailableNegative2552326 - 255280518085.4
diaminopimelate decarboxylaseBUN20_RS11170Not AvailableNegative2552876 - 255403942800.4
aspartate kinaseBUN20_RS11175Not AvailableNegative2554182 - 255550149216.4
cell division atp-binding protein ftseBUN20_RS11180Not AvailableNegative2555533 - 255623126258.7
bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp diphosphatase hisieBUN20_RS11185Not AvailableNegative2556216 - 255682723267.7
imidazole glycerol phosphate synthase subunit hisfBUN20_RS11190Not AvailableNegative2557005 - 255775726983.2
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomeraseBUN20_RS11195Not AvailableNegative2557876 - 255859526235.5
imidazole glycerol phosphate synthase subunit hishBUN20_RS11200Not AvailableNegative2558635 - 255922522200.8

Displaying genes 2171 – 2180 of 4436 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total