Escherichia coli strain SLK172

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain SLK172 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain can be found in pairs or singles and possesses flagella, allowing for mobility. It thrives optimally at 37°C and is classified as mesophilic, indicating it favors moderate temperature ranges for growth. E. coli SLK172 is predominantly host-associated and has a diverse range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals, birds, and even some plants like Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This extensive host range suggests that E. coli SLK172 can adapt to various biological environments, making it a versatile organism in different ecological niches. The strain is implicated in several health issues, particularly in humans, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions like neonatal meningitis and hemolytic uremic syndrome (HUS). These health effects underline the pathogenic potential of E. coli SLK172, which can result in significant clinical consequences. In summary, the ability of E. coli SLK172 to inhabit various hosts and its association with numerous health complications highlight its ecological significance and pathogenic capacity. Understanding this strain's biology and interactions with different hosts can provide insights into its role in health and disease, emphasizing the importance of monitoring such versatile microorganisms in clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain SLK172

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain SLK172
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain SLK172 plasmid pSLK172-2, complete

Gene Summary

Adenine Count

27900 bp

Thymine Count

29081 bp

Guanine Count

30642 bp

Cytosine Count

32905 bp

Genome Length

120528 bp

Protein-coding Genes

150 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
terd family proteinBJJ90_RS30095Not AvailablePositive221326 - 22196723575.9
vwa domain-containing proteinBJJ90_RS30100Not AvailablePositive221967 - 22260522716.1
tery-c metal binding domain-containing proteinBJJ90_RS30105Not AvailablePositive222691 - 22373138075.2
pp2c family serine/threonine-protein phosphataseBJJ90_RS30110Not AvailablePositive223731 - 22536859624.0
helix-hairpin-helix domain-containing proteinBJJ90_RS30115Not AvailablePositive225394 - 22689356869.0
hypothetical proteinBJJ90_RS30120Not AvailableNegative227060 - 22814240896.8
hha/ymoa family nucleoid-associated regulatory proteinBJJ90_RS30125Not AvailableNegative228503 - 2287158173.85
tyrosine-type recombinase/integraseBJJ90_RS30130Not AvailablePositive228886 - 23006145668.1
pap2 family proteinBJJ90_RS32395Not AvailableNegative230083 - 23117440810.1
duf5431 family proteinBJJ90_RS30145Not AvailableNegative231246 - 23224436988.5

Displaying genes 401 – 410 of 547 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total