Cutibacterium avidum strain DPC 6544

Cutibacterium avidum strain DPC 6544 is a Gram-positive, non-motile rod bacterium classified as a facultative anaerobe. This strain is categorized as a chemoheterotroph, deriving its energy from organic compounds. It is mesophilic, thriving within a temperature range suitable for growth in a variety of environments, including those associated with human hosts (Homo sapiens). One of the significant health implications of C. avidum strain DPC 6544 is its association with orthopedic infections. It is implicated in periprosthetic joint infections (PJI) and orthopedic device-related infections (ODRI), particularly in cases following hip arthroplasty. This highlights the strain's relevance in clinical settings, specifically regarding infections associated with implanted medical devices. The strain possesses one replicon and has an accession number of NZ_CP016954.1, which aids in its identification and characterization within microbial databases. Notably, C. avidum is non-sporulating, which may influence its survival strategies and interactions within host environments. The presence of flagella in this strain, despite its non-motility, suggests potential complexities in its biological functions or in interactions with host immune responses. The ecological role of C. avidum strain DPC 6544, particularly in the context of human health and infection, underscores the importance of understanding its pathogenic potential, especially in the realm of orthopedic medicine. The strain's ability to thrive in various habitats and its association with specific infections highlights the need for continued research into its biology and interactions within the human microbiome.