Lactococcus cremoris strain JM4

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Lactococcus

Description

Lactococcus cremoris strain JM4 is a Gram-positive bacterium that belongs to the genus Lactococcus. This strain exhibits a cocci shape and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is non-motile and lacks flagella, indicating a reliance on passive means for movement in its habitat. The optimal growth temperature for L. cremoris strain JM4 is 40°C, placing it within the mesophilic temperature range. This temperature preference suggests a capability to thrive in moderate environmental conditions. The strain is characterized by having one membrane and nine replicons, indicating a complex genetic structure. L. cremoris strain JM4 is free-living and has been associated with human hosts, where it is linked to health concerns such as infectious endocarditis and other human infections. Its pathogenicity underscores its potential to cause disease in humans, marking it as a strain of interest in clinical microbiology. The presence of L. cremoris strain JM4 in human-associated environments highlights its ecological role, particularly in understanding microbial interactions within the human microbiome. Its ability to thrive in varied habitats while also being linked to human infections emphasizes the dual nature of certain microorganisms, where they can exist as benign residents or become pathogenic under specific conditions. This duality is crucial for further studies in microbial ecology and human health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusLactococcus
SpeciesLactococcus cremoris
Strainstrain JM4

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Lactococcus cremoris strain JM4
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature40
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Lactococcus cremoris strain JM4 plasmid pJM4F, complete sequence.

Gene Summary

Adenine Count

4349 bp

Thymine Count

3876 bp

Guanine Count

2175 bp

Cytosine Count

2126 bp

Genome Length

12526 bp

Protein-coding Genes

17 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

9

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rhodanese-related sulfurtransferaseLLJM4_RS06885Not AvailablePositive1374983 - 137594236742.5
histidinol-phosphatase hisj family proteinLLJM4_RS06890Not AvailableNegative1375975 - 137676030295.0
bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp diphosphatase hisieLLJM4_RS06895Not AvailableNegative1376761 - 137739924755.3
imidazole glycerol phosphate synthase subunit hisfLLJM4_RS06900Not AvailableNegative1377396 - 137817527999.9
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomeraseLLJM4_RS06905Not AvailableNegative1378144 - 137888427414.0
imidazole glycerol phosphate synthase subunit hishLLJM4_RS06910Not AvailableNegative1378884 - 137949222264.4
aminoglycoside 3'-phosphotransferaseLLJM4_RS06915Not AvailableNegative1379537 - 138030730042.4
imidazoleglycerol-phosphate dehydratase hisbLLJM4_RS06920Not AvailableNegative1380319 - 138092722418.8
histidinol dehydrogenaseLLJM4_RS06925Not AvailableNegative1380928 - 138223547696.9
cation-translocating p-type atpaseLLJM4_RS06930Not AvailableNegative1382219 - 138284523374.6

Displaying genes 1471 – 1480 of 2760 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infectious endocarditisCausesPMC10064683
Human infectionsCausesPMC10064683

Displaying health effects 1 – 2 of 2 in total