Streptococcus salivarius strain ATCC 25975

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus salivarius strain ATCC 25975 is a Gram-positive cocci bacterium that typically arranges itself in chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It occupies host-associated habitats, specifically within Homo sapiens, where it can be found as a free-living organism. This strain is mesophilic, indicating it grows optimally at moderate temperatures. It possesses two replicons, which may contribute to its adaptability and genetic diversity. Notably, Streptococcus salivarius ATCC 25975 does not exhibit mobility as it lacks flagella and is nonsporulating, which means it does not form spores for reproduction or survival under adverse conditions. Despite its presence in the human microbiome, this strain is associated with various health complications, including bacteremia, pneumonia, endocarditis, peritonitis, and meningitis, highlighting its pathogenic potential. The presence of this strain in the human body underscores the complex relationship between host and microbiota, where otherwise commensal organisms can become opportunistic pathogens under certain conditions. The duality of Streptococcus salivarius ATCC 25975 as both a normal inhabitant of the human microbiome and a potential pathogen illustrates the intricate balance of microbial communities and their impact on human health. Understanding its characteristics and behaviors may provide insights into managing infections associated with this strain and highlight the importance of monitoring microbial populations in clinical settings.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus salivarius
Strainstrain ATCC 25975

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus salivarius strain ATCC 25975
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus salivarius strain ATCC 25975 chromosome, complete

Gene Summary

Adenine Count

666087 bp

Thymine Count

656415 bp

Guanine Count

438487 bp

Cytosine Count

438804 bp

Genome Length

2199793 bp

Protein-coding Genes

1982 genes

Non-Coding Genes

90 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
helix-turn-helix transcriptional regulatorV471_RS00400Not AvailableNegative80712 - 8170139079.4
hypothetical proteinV471_RS00405Not AvailableNegative81843 - 820467874.24
diacylglycerol kinaseV471_RS00410Not AvailableNegative82169 - 8318236824.2
nad-dependent dna ligase ligaV471_RS00415Not AvailableNegative83192 - 8515072055.6
quet transporter family proteinV471_RS00420Not AvailableNegative85200 - 8570918976.6
yihy/virulence factor brkb family proteinV471_RS00425Not AvailableNegative85799 - 8675836180.3
methionyl aminopeptidaseV471_RS00430Not AvailableNegative86760 - 8762031724.9
cbs-hotdog domain-containing transcription factor spxrV471_RS00435Not AvailableNegative87660 - 8894048647.0
gnat family n-acetyltransferaseV471_RS00440Not AvailableNegative88933 - 8947821107.5
udp-n-acetylglucosamine 1-carboxyvinyltransferaseV471_RS00445Not AvailableNegative89544 - 9080644715.4

Displaying genes 81 – 90 of 2186 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC11536889
BacteremiaCausesPMC11536889
EndocarditisCausesPMC11536889
MeningitisCausesPMC11536889
PeritonitisCausesPMC9615012

Displaying health effects 1 – 5 of 5 in total