Streptococcus salivarius strain ATCC 25975

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus salivarius strain ATCC 25975 is a Gram-positive cocci bacterium that typically arranges itself in chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It occupies host-associated habitats, specifically within Homo sapiens, where it can be found as a free-living organism. This strain is mesophilic, indicating it grows optimally at moderate temperatures. It possesses two replicons, which may contribute to its adaptability and genetic diversity. Notably, Streptococcus salivarius ATCC 25975 does not exhibit mobility as it lacks flagella and is nonsporulating, which means it does not form spores for reproduction or survival under adverse conditions. Despite its presence in the human microbiome, this strain is associated with various health complications, including bacteremia, pneumonia, endocarditis, peritonitis, and meningitis, highlighting its pathogenic potential. The presence of this strain in the human body underscores the complex relationship between host and microbiota, where otherwise commensal organisms can become opportunistic pathogens under certain conditions. The duality of Streptococcus salivarius ATCC 25975 as both a normal inhabitant of the human microbiome and a potential pathogen illustrates the intricate balance of microbial communities and their impact on human health. Understanding its characteristics and behaviors may provide insights into managing infections associated with this strain and highlight the importance of monitoring microbial populations in clinical settings.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus salivarius
Strainstrain ATCC 25975

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus salivarius strain ATCC 25975
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus salivarius strain ATCC 25975 chromosome, complete

Gene Summary

Adenine Count

666087 bp

Thymine Count

656415 bp

Guanine Count

438487 bp

Cytosine Count

438804 bp

Genome Length

2199793 bp

Protein-coding Genes

1982 genes

Non-Coding Genes

90 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tetr/acrr family transcriptional regulatorV471_RS09535Not AvailableNegative2029957 - 203049920930.4
mdr family mfs transporterV471_RS09540Not AvailablePositive2030671 - 203243763729.6
lysr family transcriptional regulatorV471_RS09545Not AvailablePositive2032490 - 203322128133.7
glycosyltransferase family 2 proteinV471_RS09550Not AvailableNegative2033206 - 203422540131.7
copper homeostasis protein cutcV471_RS09555Not AvailableNegative2034701 - 203533622894.6
tetr/acrr family transcriptional regulatorV471_RS09560Not AvailableNegative2035374 - 203594321627.2
degv family proteinV471_RS09565Not AvailablePositive2036082 - 203691230167.2
mfs transporterV471_RS09570Not AvailablePositive2037142 - 203831441880.3
alpha/beta hydrolaseV471_RS09575Not AvailableNegative2038379 - 203915529513.8
helix-turn-helix domain-containing proteinV471_RS09580Not AvailablePositive2039451 - 204033833254.8

Displaying genes 1911 – 1920 of 2186 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC11536889
BacteremiaCausesPMC11536889
EndocarditisCausesPMC11536889
MeningitisCausesPMC11536889
PeritonitisCausesPMC9615012

Displaying health effects 1 – 5 of 5 in total