Streptococcus salivarius strain ATCC 25975

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus salivarius strain ATCC 25975 is a Gram-positive cocci bacterium that typically arranges itself in chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It occupies host-associated habitats, specifically within Homo sapiens, where it can be found as a free-living organism. This strain is mesophilic, indicating it grows optimally at moderate temperatures. It possesses two replicons, which may contribute to its adaptability and genetic diversity. Notably, Streptococcus salivarius ATCC 25975 does not exhibit mobility as it lacks flagella and is nonsporulating, which means it does not form spores for reproduction or survival under adverse conditions. Despite its presence in the human microbiome, this strain is associated with various health complications, including bacteremia, pneumonia, endocarditis, peritonitis, and meningitis, highlighting its pathogenic potential. The presence of this strain in the human body underscores the complex relationship between host and microbiota, where otherwise commensal organisms can become opportunistic pathogens under certain conditions. The duality of Streptococcus salivarius ATCC 25975 as both a normal inhabitant of the human microbiome and a potential pathogen illustrates the intricate balance of microbial communities and their impact on human health. Understanding its characteristics and behaviors may provide insights into managing infections associated with this strain and highlight the importance of monitoring microbial populations in clinical settings.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus salivarius
Strainstrain ATCC 25975

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus salivarius strain ATCC 25975
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus salivarius strain ATCC 25975 chromosome, complete

Gene Summary

Adenine Count

666087 bp

Thymine Count

656415 bp

Guanine Count

438487 bp

Cytosine Count

438804 bp

Genome Length

2199793 bp

Protein-coding Genes

1982 genes

Non-Coding Genes

90 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
spy0128 family proteinV471_RS05730Not AvailablePositive1135846 - 1149132485906.0
zmpa/zmpb/zmpc family metallo-endopeptidaseV471_RS05735Not AvailablePositive1149601 - 1155543217703.0
mucin-binding proteinV471_RS05740Not AvailablePositive1156000 - 1159164111557.0
exonuclease sbccd subunit dV471_RS05745Not AvailablePositive1159351 - 116055945706.9
aaa family atpaseV471_RS05750Not AvailablePositive1160556 - 1163735119997.0
lysr family transcriptional regulatorV471_RS05755Not AvailablePositive1164092 - 11643438894.73
catb-related o-acetyltransferaseV471_RS05760Not AvailablePositive1164729 - 116559833295.0
glycosyltransferaseV471_RS05765Not AvailablePositive1165723 - 116781681735.9
acyltransferaseV471_RS05770Not AvailablePositive1167818 - 116869332767.9
glycosyltransferase family 8 proteinV471_RS05775Not AvailablePositive1168835 - 116986640338.8

Displaying genes 1141 – 1150 of 2186 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC11536889
BacteremiaCausesPMC11536889
EndocarditisCausesPMC11536889
MeningitisCausesPMC11536889
PeritonitisCausesPMC9615012

Displaying health effects 1 – 5 of 5 in total