Escherichia coli strain 28RC1

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 28RC1 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain is notable for its mobility, facilitated by the presence of flagella, and is typically found in pairs or as single cells. It thrives at an optimal temperature of 37°C, indicating its mesophilic nature, and is associated with a variety of hosts, including humans (Homo sapiens), domestic animals like chickens (Gallus gallus) and cattle (Bos taurus), as well as various other vertebrates and invertebrates. E. coli strain 28RC1 is recognized for its potential pathogenicity, particularly in humans, where it can cause a range of health issues such as urinary tract infections (UTIs), gastrointestinal infections, and severe conditions like hemolytic uremic syndrome (HUS) and neonatal meningitis. The strain's ability to impact multiple organ systems underscores its clinical significance. In terms of its ecological role, E. coli strain 28RC1 can be categorized as free-living, suggesting that it may not only thrive within host organisms but also exist independently in various environments. This adaptability could potentially facilitate its transmission between different hosts, contributing to its prevalence in both human and veterinary medicine. Understanding the biotic relationships and pathogenic capabilities of this strain can provide insights into the management of infections it causes, highlighting the importance of monitoring its spread and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 28RC1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 28RC1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 28RC1


Gene Summary

Adenine Count

1377407 bp

Thymine Count

1371115 bp

Guanine Count

1411082 bp

Cytosine Count

1402094 bp

Genome Length

5561698 bp

Protein-coding Genes

4589 genes

Non-Coding Genes

1027 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinARC77_RS00010Not AvailablePositive589 - 8018259.02
Putative portal proteinARC77_RS33270Not AvailablePositive801 - 229552022.4
Head maturation proteaseARC77_RS33275Not AvailablePositive2240 - 425672420.9
Hypothetical proteinARC77_RS33280Not AvailablePositive4344 - 465810359.2
Hypothetical proteinARC77_RS33285Not AvailablePositive4662 - 494210259.7
Putative minor tail proteinARC77_RS32325Not AvailablePositive4945 - 556722059.9
phage tail terminator proteinARC77_RS00040Not AvailablePositive5564 - 597614418.6
Major tail protein vARC77_RS00045Not AvailablePositive5984 - 673727052.4
Putative minor tail proteinARC77_RS00050Not AvailablePositive6751 - 717315851.7
Putative minor tail proteinARC77_RS00055Not AvailablePositive7200 - 750211485.4

Displaying genes 1 – 10 of 5708 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 74 in total