Streptococcus mitis strain SVGS_061

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain SVGS_061 is a Gram-positive, cocci-shaped bacterium that is typically found in chains or pairs. This strain is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. It is non-motile, lacking flagella, and possesses a single membrane structure. With a mesophilic temperature range, S. mitis SVGS_061 is adapted to moderate temperature conditions, typical of its host-associated habitat. This strain is free-living and primarily associated with Homo sapiens, where it can be part of the normal microbiota. However, it is also known to have significant health implications. S. mitis has been linked to various infections, including endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. These associations highlight the dual role of S. mitis as a commensal organism in humans and a potential opportunistic pathogen. The presence of only one replicon in S. mitis SVGS_061 suggests a streamlined genomic organization, which may contribute to its adaptability within the human host. The strain's ability to thrive in diverse environments, coupled with its pathogenic potential, underscores the importance of monitoring and understanding such microorganisms in clinical settings. Their role in both health and disease emphasizes the need for further research into their ecological interactions and mechanisms of pathogenicity.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain SVGS_061

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain SVGS_061
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain SVGS_061


Gene Summary

Adenine Count

656176 bp

Thymine Count

645262 bp

Guanine Count

437317 bp

Cytosine Count

429167 bp

Genome Length

2167922 bp

Protein-coding Genes

1874 genes

Non-Coding Genes

144 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive15093 - 15104Not Available
Gp260AXK38_RS00115Q04N48Positive21653 - 2293947546.6
IntegraseAXK38_RS00120Not AvailableNegative23202 - 2435044353.3
Hypothetical proteinAXK38_RS00125Not AvailableNegative24659 - 2540228219.8
Gp2AXK38_RS11480Not AvailableNegative25508 - 2593916439.6
Duf955 domain proteinAXK38_RS00135Not AvailableNegative25951 - 2633415140.0
Hypothetical proteinAXK38_RS00140Not AvailableNegative26347 - 2671213748.5
AttlNot AvailableNot AvailablePositive26937 - 26948Not Available
Gp8AXK38_RS00145Not AvailablePositive26999 - 272088028.82
Prophage antirepressor proteinAXK38_RS00150Q91FN5Positive27212 - 2792226820.0

Displaying genes 1 – 10 of 2018 in total

Metabolites

99 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm0000719chloramphenicol 3-acetateC13H14Cl2N2O6Chemical structure of chloramphenicol 3-acetateNot available
Average365.16Da
Monoisotopic364.0228916Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da

Displaying 1–10 of 99 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055

Displaying health effects 1 – 5 of 5 in total