Legionella pneumophila subsp. pascullei strain D-7119

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila subsp. pascullei strain D-7119 is a Gram-negative, rod-shaped bacterium that is aerobic and chemoorganotrophic. It exhibits mobility, characterized by the presence of flagella, and typically exists as single cells. This strain is mesophilic, thriving within a moderate temperature range. The ecological niche of strain D-7119 is primarily host-associated, with a diverse array of hosts including Homo sapiens, various plant species (Viridiplantae), and several amoebae such as Acanthamoeba castellanii and Balamuthia mandrillaris. It also interacts with social amoebae like Dictyostelium discoideum, demonstrating its ability to inhabit various biological environments. In terms of health impacts, Legionella pneumophila subsp. pascullei strain D-7119 is known to cause several serious diseases in humans, including Legionnaires' disease, which is a form of pneumonia, as well as other respiratory illnesses such as community-acquired pneumonia (CAP) and atypical pneumonia. It is associated with both mild and severe health effects, including endocarditis. This strain is nonsporulating and has a single replicon and a double membrane structure, which is characteristic of its classification within the Legionella genus. Given its pathogenic potential and association with different hosts, Legionella pneumophila subsp. pascullei strain D-7119 underscores the importance of monitoring water systems and environments where these bacteria may thrive, as they can pose significant public health risks through aerosolized water or contaminated environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainsubsp. pascullei strain D-7119

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila subsp. pascullei strain D-7119
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila subsp. pascullei strain D-7119 chromosome,

Gene Summary

Adenine Count

1046988 bp

Thymine Count

1042510 bp

Guanine Count

644979 bp

Cytosine Count

642159 bp

Genome Length

3376636 bp

Protein-coding Genes

2971 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
4-phosphoerythronate dehydrogenaseAXF37_RS04670Not AvailableNegative1018172 - 101924539854.9
site-2 protease family proteinAXF37_RS04675Not AvailableNegative1019242 - 101990124179.9
phosphatase pap2 family proteinAXF37_RS04680Not AvailablePositive1020223 - 102086125216.4
hypothetical proteinAXF37_RS04685Not AvailablePositive1020901 - 102214547021.9
electron transfer flavoprotein subunit beta/fixa family proteinAXF37_RS04690Not AvailablePositive1022367 - 102311627416.5
electron transfer flavoprotein subunit alpha/fixb family proteinAXF37_RS04695Not AvailablePositive1023130 - 102406833451.1
alanine dehydrogenaseAXF37_RS04700Not AvailablePositive1024080 - 102520139226.4
penicillin-binding protein 1aAXF37_RS04705Not AvailableNegative1025261 - 102764588697.7
hypothetical proteinAXF37_RS04710Not AvailableNegative1027796 - 102880938056.6
pilus assembly protein pilmAXF37_RS04715Not AvailablePositive1029228 - 103029238797.1

Displaying genes 931 – 940 of 3027 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total