Legionella pneumophila subsp. pascullei strain D-7119

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila subsp. pascullei strain D-7119 is a Gram-negative, rod-shaped bacterium that is aerobic and chemoorganotrophic. It exhibits mobility, characterized by the presence of flagella, and typically exists as single cells. This strain is mesophilic, thriving within a moderate temperature range. The ecological niche of strain D-7119 is primarily host-associated, with a diverse array of hosts including Homo sapiens, various plant species (Viridiplantae), and several amoebae such as Acanthamoeba castellanii and Balamuthia mandrillaris. It also interacts with social amoebae like Dictyostelium discoideum, demonstrating its ability to inhabit various biological environments. In terms of health impacts, Legionella pneumophila subsp. pascullei strain D-7119 is known to cause several serious diseases in humans, including Legionnaires' disease, which is a form of pneumonia, as well as other respiratory illnesses such as community-acquired pneumonia (CAP) and atypical pneumonia. It is associated with both mild and severe health effects, including endocarditis. This strain is nonsporulating and has a single replicon and a double membrane structure, which is characteristic of its classification within the Legionella genus. Given its pathogenic potential and association with different hosts, Legionella pneumophila subsp. pascullei strain D-7119 underscores the importance of monitoring water systems and environments where these bacteria may thrive, as they can pose significant public health risks through aerosolized water or contaminated environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainsubsp. pascullei strain D-7119

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila subsp. pascullei strain D-7119
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila subsp. pascullei strain D-7119


Gene Summary

Adenine Count

1046988 bp

Thymine Count

1042510 bp

Guanine Count

644979 bp

Cytosine Count

642159 bp

Genome Length

3376636 bp

Protein-coding Genes

2971 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tlpa disulfide reductase family proteinAXF37_RS00055Not AvailableNegative14060 - 1453017882.8
dot/icm t4ss effector cegc1AXF37_RS00060Not AvailableNegative14699 - 1627660250.7
pirin family proteinAXF37_RS00065Not AvailablePositive16420 - 1725930880.0
patatin-like phospholipase family proteinAXF37_RS00070Not AvailablePositive17696 - 1890745440.4
hlyd family secretion proteinAXF37_RS00075Not AvailablePositive19008 - 2008140669.4
hypothetical proteinAXF37_RS00080Not AvailablePositive20056 - 2098836267.3
fusc family proteinAXF37_RS00085Not AvailablePositive20973 - 2187835122.9
tolc family proteinAXF37_RS00090Not AvailablePositive21862 - 2324751958.9
m4 family metallopeptidaseAXF37_RS00095Not AvailablePositive23482 - 2515862018.8
hypothetical proteinAXF37_RS00100Not AvailablePositive25378 - 2628932797.9

Displaying genes 11 – 20 of 3027 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total