Campylobacter coli strain OR12

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter coli strain OR12 is a Gram-negative microaerophilic bacterium known to cause a variety of health effects in its hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), and Bos (cattle). The strain is associated with multiple clinical conditions such as bloodstream infections, urinary tract infections, intestinal campylobacteriosis, enteritis, and other diarrheal diseases, highlighting its pathogenic potential. This strain possesses four replicons, which may contribute to its adaptability and virulence. The presence of multiple replicons can facilitate the acquisition of genetic material, potentially enhancing the bacterium's ability to persist and infect various hosts. Its microaerophilic nature indicates that it thrives in environments with reduced oxygen levels, which is typical for its ecological niches, such as the intestines of animals and humans. The diverse range of health effects linked to Campylobacter coli strain OR12 underscores its significance in public health. It is a common cause of acute bacterial enteritis, which can lead to significant morbidity. In addition, the strain's ability to infect multiple host species suggests its ecological versatility and potential role in zoonotic transmission, where infections can be transferred from animals to humans. Overall, the pathogenic characteristics and host range of Campylobacter coli strain OR12 emphasize the need for continued surveillance and research to understand its epidemiology and the risk it poses to human health. The strain's genetic adaptability may also provide insights into the mechanisms of bacterial evolution and the emergence of new pathogenic strains.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter coli
Strainstrain OR12

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Campylobacter coli strain OR12
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Campylobacter coli strain OR12 plasmid pOR12TET, complete

Gene Summary

Adenine Count

11085 bp

Thymine Count

9310 bp

Guanine Count

4046 bp

Cytosine Count

3540 bp

Genome Length

27981 bp

Protein-coding Genes

32 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinATE51_RS06730Not AvailablePositive1311700 - 1315638153310.0
hypothetical proteinATE51_RS06735Not AvailablePositive1315657 - 131692549207.1
fha domain-containing proteinATE51_RS06740Not AvailableNegative1316929 - 131782834711.3
type vi secretion system membrane subunit tssmATE51_RS06745Not AvailableNegative1317825 - 1321352137359.0
hcp family type vi secretion system effectorATE51_RS06750Not AvailablePositive1321470 - 132198518750.9
type ivb secretion system protein icmh/dotuATE51_RS06755Not AvailableNegative1322239 - 132301230109.8
type vi secretion system baseplate subunit tsskATE51_RS06760Not AvailableNegative1323009 - 132440653748.7
type vi secretion system lipoprotein tssjATE51_RS06765Not AvailableNegative1324416 - 132486216732.3
type vi secretion system domain-containing proteinATE51_RS06770Not AvailablePositive1324988 - 132623549531.9
type vi secretion system contractile sheath small subunitATE51_RS06775Not AvailablePositive1326304 - 132678918173.2

Displaying genes 1511 – 1520 of 2304 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Intestinal campylobacteriosisCausesPMC10942002
CampylobacteriosisCausesPMC11434686
Diarrheal diseasesCausesPMC11434686
EnteritisCausesPMC13255289
Bloodstream infectionsCausesPMC13255289
Urinary tract infectionsCausesPMC13255289
Bacterial enteritisCausesPMC4108124
Acute bacterial enteritisCausesPMC4108124
Enteric diseaseCausesPMC9565744
CampylobacteriosisCausesPMC9565744

Displaying health effects 1 – 10 of 12 in total