Campylobacter coli strain OR12

Gram-negativeMicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter coli strain OR12 is a Gram-negative microaerophilic bacterium known to cause a variety of health effects in its hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), and Bos (cattle). The strain is associated with multiple clinical conditions such as bloodstream infections, urinary tract infections, intestinal campylobacteriosis, enteritis, and other diarrheal diseases, highlighting its pathogenic potential. This strain possesses four replicons, which may contribute to its adaptability and virulence. The presence of multiple replicons can facilitate the acquisition of genetic material, potentially enhancing the bacterium's ability to persist and infect various hosts. Its microaerophilic nature indicates that it thrives in environments with reduced oxygen levels, which is typical for its ecological niches, such as the intestines of animals and humans. The diverse range of health effects linked to Campylobacter coli strain OR12 underscores its significance in public health. It is a common cause of acute bacterial enteritis, which can lead to significant morbidity. In addition, the strain's ability to infect multiple host species suggests its ecological versatility and potential role in zoonotic transmission, where infections can be transferred from animals to humans. Overall, the pathogenic characteristics and host range of Campylobacter coli strain OR12 emphasize the need for continued surveillance and research to understand its epidemiology and the risk it poses to human health. The strain's genetic adaptability may also provide insights into the mechanisms of bacterial evolution and the emergence of new pathogenic strains.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter coli
Strainstrain OR12

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Campylobacter coli strain OR12
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophile
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Campylobacter coli strain OR12 plasmid pOR12TET, complete

Gene Summary

Adenine Count

11085 bp

Thymine Count

9310 bp

Guanine Count

4046 bp

Cytosine Count

3540 bp

Genome Length

27981 bp

Protein-coding Genes

32 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nitrate reductase cytochrome c-type subunitATE51_RS05175Not AvailableNegative1021984 - 102250818864.4
quinol dehydrogenase ferredoxin subunit naphATE51_RS05180Not AvailableNegative1022505 - 102329029424.1
ferredoxin-type protein napgATE51_RS05185Not AvailableNegative1023287 - 102402727332.0
periplasmic nitrate reductase subunit alphaATE51_RS05190Not AvailableNegative1024045 - 1026819105076.0
thiol peroxidaseATE51_RS05195Not AvailableNegative1027088 - 102761518274.1
modification methylaseATE51_RS05200Not AvailableNegative1027724 - 102845527047.5
atp-dependent helicaseATE51_RS05205Not AvailableNegative1028511 - 103054177196.9
hypothetical proteinATE51_RS05210Not AvailablePositive1030663 - 103159235879.8
valine--trna ligaseATE51_RS05215Not AvailablePositive1031617 - 1034229100963.0
methionine abc transporter atp-binding proteinATE51_RS05220Not AvailablePositive1034235 - 103524537766.2

Displaying genes 1191 – 1200 of 2304 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Intestinal campylobacteriosisCausesPMC10942002
CampylobacteriosisCausesPMC11434686
Diarrheal diseasesCausesPMC11434686
EnteritisCausesPMC13255289
Bloodstream infectionsCausesPMC13255289
Urinary tract infectionsCausesPMC13255289
Bacterial enteritisCausesPMC4108124
Acute bacterial enteritisCausesPMC4108124
Enteric diseaseCausesPMC9565744
CampylobacteriosisCausesPMC9565744

Displaying health effects 1 – 10 of 12 in total