Helicobacter pylori strain 29CaP

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 29CaP is a Gram-negative, microaerophilic bacterium characterized by its spiral shape and occurrence as single cells. This strain thrives optimally at a temperature of 37.0°C, suggesting an adaptation to the warm environment of the host's gastric mucosa. As a host-associated organism, H. pylori strain 29CaP is likely to play a role in the complex microbial community of the stomach, where it may influence local pH and contribute to the host's gastrointestinal health. The microaerophilic nature of this strain indicates that it requires reduced levels of oxygen for growth, which aligns with its habitat in the oxygen-limited environment of the gastric epithelium. This unique adaptation aids in its survival and proliferation within the host, potentially impacting the overall composition of the gastric microbiome. Understanding the specific traits of Helicobacter pylori strain 29CaP provides insight into its ecological niche and the evolutionary pressures that shape its physiology. The interplay between its microaerophilic requirement and host-associated lifestyle may influence not only its survival strategies but also its interactions with other microbial inhabitants of the stomach, highlighting the intricate dynamics of host-microbe relationships in gastrointestinal ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 29CaP

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 29CaP
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 29CaP


Gene Summary

Adenine Count

491352 bp

Thymine Count

499248 bp

Guanine Count

311836 bp

Cytosine Count

321991 bp

Genome Length

1624441 bp

Protein-coding Genes

1511 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
transcription antitermination factor nusbAPV63_RS00005B5Z6D7-89 - 50515520.0
6,7-dimethyl-8-ribityllumazine synthaseAPV63_RS00010B6JPA1-507 - 97716970.7
3-deoxy-8-phosphooctulonate synthaseAPV63_RS00015Q9ZN55-987 - 181730363.7
carbonic anhydraseAPV63_RS00020Q9ZN54-1804 - 246925894.0
orotidine-5'-phosphate decarboxylaseAPV63_RS00025B2UW09+2592 - 327525396.2
pantoate--beta-alanine ligaseAPV63_RS00030B6JPA5+3276 - 410631180.2
Trna-gluNot AvailableNot Available+4120 - 4195Not Available
Trna-aspNot AvailableNot Available+4255 - 4331Not Available
Trna-valNot AvailableNot Available+4372 - 4447Not Available
Trna-gluNot AvailableNot Available+4488 - 4562Not Available

Displaying genes 1 – 10 of 3172 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

94 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 94 metabolites