Helicobacter pylori strain 7C

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 7C is a Gram-negative bacterium characterized by its distinctive spirilla shape and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, which aligns with its adaptation to the human gastric environment. As a microaerophilic organism, H. pylori strain 7C requires reduced levels of oxygen for growth, reflecting its specialized niche within the host-associated habitat of the stomach. The microbe's spiral morphology may contribute to its ability to navigate the viscous mucus layer of the gastric epithelium, facilitating colonization and persistence in a challenging environment characterized by acidic pH levels. Given its specific oxygen requirements and optimal growth temperature, H. pylori strain 7C likely exhibits metabolic adaptations that enable it to survive and thrive in the unique conditions of the gastric milieu. Understanding the physiological traits of H. pylori strain 7C can provide insights into its ecological role in the human stomach, where it may influence gastric microbiota composition and host health. The microbe's microaerophilic nature suggests a potential interplay with other gut microorganisms, highlighting the intricate balance of microbial communities in the human gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 7C

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 7C
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 7C


Gene Summary

Adenine Count

1976 bp

Thymine Count

2362 bp

Guanine Count

1275 bp

Cytosine Count

1222 bp

Genome Length

6835 bp

Protein-coding Genes

4 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
relaxase/mobilization nuclease domain-containing proteinAPV63_RS07755P07047-144 - 215979172.9
plasmid mobilization relaxosome protein mobcAPV63_RS08715Not Available-2149 - 22714603.45
rna-guided endonuclease tnpb family proteinAPV63_RS07760P54992-2281 - 356449451.0
is200/is605 family transposaseAPV63_RS07765Not Available+3616 - 406217604.6

Displaying genes 1 – 4 of 4 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

16 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm0001086scyllo-inososeC6H10O6Chemical structure of scyllo-inososeNot available
Average178.14Da
Monoisotopic178.0477381Da
BASm0001358lactateC3H5O3Chemical structure of lactateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002002glyoxylateC2HO3Chemical structure of glyoxylateNot available
Average73.0275Da
Monoisotopic72.9925689Da
BASm0002411(S)-benzoinC14H12O2Chemical structure of (S)-benzoinNot available
Average212.248Da
Monoisotopic212.083729626Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da
BASm0002984N-carbamoyl-2-oxoglycineC3H3N2O4Chemical structure of N-carbamoyl-2-oxoglycineNot available
Average131.068Da
Monoisotopic131.0098302Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da

Displaying 1–10 of 16 metabolites