Streptococcus mitis strain KCOM 1350 (= ChDC B183)

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain KCOM 1350, also known as ChDC B183, is a Gram-positive, cocci-shaped bacterium that typically arranges itself in chains or pairs. This strain is classified as a facultative anaerobe, meaning it can grow in both aerobic and anaerobic environments. It is non-motile and does not possess flagella, which contributes to its stable presence in host-associated habitats. This strain is mesophilic, thriving within a moderate temperature range conducive to growth. S. mitis strain KCOM 1350 has one replicon and is characterized by a single membrane structure. It is categorized as free-living, indicating its ability to exist independently, although it is commonly associated with Homo sapiens as a host. Clinically, S. mitis has significant health implications, being implicated in various serious conditions such as endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. These associations highlight its pathogenic potential, particularly in immunocompromised individuals or those with underlying health conditions. Understanding the ecological role and pathogenicity of Streptococcus mitis strain KCOM 1350 can provide insights into its contribution to human health and disease. Given its prevalence in the human microbiome, monitoring and studying this strain may aid in developing strategies for preventing and managing the infections it can cause. The strain's accessions, such as NZ_CP012646.1, facilitate further research and characterization of its genetic and phenotypic traits.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain KCOM 1350 (= ChDC B183)

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain KCOM 1350 (= ChDC B183)
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain KCOM 1350 (= ChDC B183) chromosome,

Gene Summary

Adenine Count

575439 bp

Thymine Count

564326 bp

Guanine Count

383155 bp

Cytosine Count

383424 bp

Genome Length

1906344 bp

Protein-coding Genes

1807 genes

Non-Coding Genes

55 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinRN80_RS00210Not AvailableNegative34259 - 3457911863.3
polyketide cyclaseRN80_RS10050Not AvailableNegative34594 - 347013781.52
hypothetical proteinRN80_RS00215Not AvailableNegative34874 - 3527815681.0
cpbp family intramembrane glutamic endopeptidaseRN80_RS00220Not AvailableNegative35339 - 3600725235.8
pncf family bacteriocin immunity proteinRN80_RS10055Not AvailableNegative36365 - 364844586.72
sensor histidine kinaseRN80_RS00235Not AvailableNegative37187 - 3853652251.1
lyttr family dna-binding domain-containing proteinRN80_RS00240Not AvailableNegative38550 - 3928728846.5
hypothetical proteinRN80_RS00245Not AvailablePositive39583 - 3991212355.8
abc transporter permeaseRN80_RS00250Not AvailableNegative39974 - 4102340449.0
abc transporter atp-binding proteinRN80_RS00255Not AvailableNegative41020 - 4175127100.2

Displaying genes 41 – 50 of 1862 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total