Streptococcus mitis strain KCOM 1350 (= ChDC B183)

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain KCOM 1350, also known as ChDC B183, is a Gram-positive, cocci-shaped bacterium that typically arranges itself in chains or pairs. This strain is classified as a facultative anaerobe, meaning it can grow in both aerobic and anaerobic environments. It is non-motile and does not possess flagella, which contributes to its stable presence in host-associated habitats. This strain is mesophilic, thriving within a moderate temperature range conducive to growth. S. mitis strain KCOM 1350 has one replicon and is characterized by a single membrane structure. It is categorized as free-living, indicating its ability to exist independently, although it is commonly associated with Homo sapiens as a host. Clinically, S. mitis has significant health implications, being implicated in various serious conditions such as endocarditis, peritonitis, invasive streptococcal disease, and S. mitis meningitis. These associations highlight its pathogenic potential, particularly in immunocompromised individuals or those with underlying health conditions. Understanding the ecological role and pathogenicity of Streptococcus mitis strain KCOM 1350 can provide insights into its contribution to human health and disease. Given its prevalence in the human microbiome, monitoring and studying this strain may aid in developing strategies for preventing and managing the infections it can cause. The strain's accessions, such as NZ_CP012646.1, facilitate further research and characterization of its genetic and phenotypic traits.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
Strainstrain KCOM 1350 (= ChDC B183)

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis strain KCOM 1350 (= ChDC B183)
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain KCOM 1350 (= ChDC B183) chromosome,

Gene Summary

Adenine Count

575439 bp

Thymine Count

564326 bp

Guanine Count

383155 bp

Cytosine Count

383424 bp

Genome Length

1906344 bp

Protein-coding Genes

1807 genes

Non-Coding Genes

55 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinRN80_RS00840Not AvailableNegative152434 - 1525865524.85
polc-type dna polymerase iiiRN80_RS00845Not AvailableNegative152610 - 157001164626.0
elongation factor gRN80_RS00850Not AvailableNegative157105 - 15918676807.3
30s ribosomal protein s7RN80_RS00855Not AvailableNegative159436 - 15990617757.4
30s ribosomal protein s12RN80_RS00860Not AvailableNegative159926 - 16033915144.6
response regulator transcription factorRN80_RS00865Not AvailableNegative160654 - 16125322278.9
sensor histidine kinaseRN80_RS00870Not AvailableNegative161255 - 16235242122.1
abc transporter permeaseRN80_RS00875Not AvailableNegative162352 - 16308927348.3
abc transporter atp-binding proteinRN80_RS00880Not AvailableNegative163091 - 16397533537.4
hypothetical proteinRN80_RS00885Not AvailableNegative163962 - 1641567706.53

Displaying genes 161 – 170 of 1862 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total