Escherichia coli strain 06-00048

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 06-00048 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, capable of thriving in both aerobic and anaerobic environments. This strain exhibits mobility and possesses flagella, which contributes to its ability to move within its host-associated habitats. The optimal growth temperature for E. coli 06-00048 is 37°C, placing it within the mesophilic temperature range. This strain is free-living but has a diverse range of hosts, including Homo sapiens (humans), various livestock such as Gallus gallus (chickens) and Bos taurus (cattle), as well as other mammals and even some plants like Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). E. coli 06-00048 is known to cause a variety of health issues, particularly in humans, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The strain's pathogenicity is primarily associated with human hosts, leading to various complications including diarrhea, peritonitis, and septicemia. Understanding the broad host range and health impacts of E. coli 06-00048 can provide insights into the ecological interactions between this bacterium and its hosts, as well as the potential for zoonotic transmission. Its presence in both human and animal populations underscores the importance of monitoring this strain in public health and veterinary contexts to mitigate its associated risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 06-00048

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 06-00048
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 06-00048


Gene Summary

Adenine Count

57677 bp

Thymine Count

58195 bp

Guanine Count

52255 bp

Cytosine Count

45720 bp

Genome Length

213847 bp

Protein-coding Genes

239 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
is3 family transposaseGJ11_RS00855Not AvailablePositive11939 - 120915786.08
is3 family transposaseGJ11_RS00860P50360Positive12124 - 1253715485.4
formate dehydrogenase-n subunit gammaGJ11_RS00865P0AEK8Negative12629 - 1328225390.9
formate dehydrogenase subunit betaGJ11_RS00870P0AAJ3Negative13275 - 1416232410.7
formate dehydrogenase-n subunit alphaGJ11_RS00875P24183Negative14175 - 17225113451.0
hypothetical proteinGJ11_RS00880Not AvailableNegative17582 - 177586483.81
hypothetical proteinGJ11_RS29510P0A1V2Positive17890 - 180214934.77
is21-like element helper atpase istbGJ11_RS00885P15026Negative18065 - 1884729431.7
is3 family transposaseGJ11_RS00890Not AvailableNegative18844 - 1984438270.5
is3 family transposaseGJ11_RS00895Q79CE8Positive19858 - 2034318395.0

Displaying genes 11 – 20 of 239 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total