Klebsiella oxytoca strain CAV1374

Klebsiella oxytoca strain CAV1374 is a Gram-negative, non-motile, rod-shaped bacterium that functions as a facultative anaerobe, allowing it to thrive in varied oxygen conditions. As a chemoheterotroph, it derives energy from organic compounds, which is typical for many pathogenic bacteria. This strain is mesophilic, with an optimal growth temperature of 37°C, making it well-adapted to the human body and other environments with similar thermal conditions. K. oxytoca CAV1374 is associated with multiple hosts, including Homo sapiens, various Metazoa, and Viridiplantae such as Triticum aestivum (wheat) and Ovis aries (sheep). This broad host range suggests that it can inhabit diverse ecological niches, potentially impacting both human health and agricultural systems. The clinical significance of this strain is notable, as it is linked to various health issues, including septicaemia, urinary tract infections, otitis media, and nosocomial bronchopneumonia. It is also implicated in antibiotic-associated conditions such as haemorrhagic colitis and diarrhoea. Its involvement in catheter-associated urinary tract infections highlights its role as an opportunistic pathogen, particularly in healthcare settings. K. oxytoca CAV1374 does not form spores, which may influence its survival strategies in host environments. The presence of multiple replicons—11 in total—could also suggest a complex genetic adaptability, potentially contributing to its pathogenicity and resistance to antibiotics. Understanding the traits and behaviors of this strain can provide insights into its ecological roles and implications for public health.