Helicobacter pylori strain CC33C

Helicobacter pylori strain CC33C is a microaerophilic, Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This strain is notably associated with various hosts, including Homo sapiens, Gallus gallus, and other mammals, as well as certain protozoa. It possesses flagella, which aids in its mobility, although it is classified as non-motile in practical terms. The optimal growth temperature for strain CC33C is 37°C, situating it within the mesophilic temperature range. It has a biotic relationship described as free-living and contains one replicon and two membranes, typical features of this genus. Helicobacter pylori CC33C is well-documented for its significant health impacts in humans, contributing to conditions such as chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, including gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. It is also associated with a range of gastrointestinal diseases, including GERD and dyspepsia. The bacterium’s pathogenicity highlights its role as a critical player in gastrointestinal health and disease, affecting the stomach lining and leading to serious complications, including peptic ulcer disease and intestinal metaplasia. Given its widespread prevalence and association with severe health outcomes, Helicobacter pylori strain CC33C underscores the importance of understanding microbial interactions within human hosts and the potential for microbial management in preventing gastrointestinal diseases.