Salmonella enterica subsp. enterica serovar Typhimurium strain

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Salmonella

Description

Salmonella enterica subsp. enterica serovar Typhimurium is a significant pathogen known for its role in foodborne illnesses. This Gram-negative bacterium is characterized by its spirilla shape and microaerophilic oxygen requirement, thriving optimally at 37°C within a mesophilic temperature range. It is a chemoorganotroph, deriving energy from organic compounds, and is typically found in chains or singles. S. Typhimurium is associated with a variety of hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), and other metazoans as well as several plant species such as Solanum lycopersicum (tomatoes) and Hordeum vulgare (barley). This wide host range reflects its ecological adaptability and potential for transmission across different trophic levels. The strain is nonsporulating and possesses six replicons along with two membranes, which is characteristic of its Gram-negative classification. Although it does not exhibit mobility, it does possess flagella, facilitating its movement in viscous environments. The bacterium is known to cause various health effects in humans, including acute gastroenteritis, bacteremia, and systemic infections, underscoring its public health significance. Ecologically, S. Typhimurium's ability to colonize both animal and plant hosts illustrates its versatility and poses challenges for food safety and public health. Its presence in the food chain highlights the importance of proper food handling and hygiene practices to prevent outbreaks of salmonellosis and related illnesses.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusSalmonella
SpeciesSalmonella enterica
Strainsubsp. enterica serovar Typhimurium strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Salmonella enterica subsp. enterica serovar Typhimurium strain
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Singles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Salmonella enterica subsp. enterica serovar Typhimurium strain

Gene Summary

Adenine Count

12373 bp

Thymine Count

12428 bp

Guanine Count

8391 bp

Cytosine Count

9007 bp

Genome Length

42199 bp

Protein-coding Genes

54 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
spi-2 type iii secretion system chaperone sseaAU613_15910Not AvailablePositive3112358 - 311268412450.2
spi-2 type iii secretion system translocon protein ssebAU613_15915Not AvailablePositive3112691 - 311328121496.5
cesd/sycd/lcrh family type iii secretion system chaperone sscaAU613_15920Not AvailablePositive3113278 - 311375118135.8
spi-2 type iii secretion system translocon protein ssecAU613_15925Not AvailablePositive3113754 - 311520852780.4
spi-2 type iii secretion system translocon protein ssedAU613_15930Not AvailablePositive3115224 - 311581120593.2
pathogenicity island 2 effector protein sseeAU613_15935Not AvailablePositive3115814 - 311623016267.4
cesd/sycd/lcrh family type iii secretion system chaperoneAU613_15940Not AvailablePositive3116282 - 311671616375.7
type iii secretion systems effector ssefAU613_15945Not AvailablePositive3116732 - 311751426727.2
pathogenicity island 2 effector protein ssegAU613_15950Not AvailablePositive3117511 - 311820024369.9
type iii secretion system needle protein ssagAU613_15955Not AvailablePositive3118294 - 31185097944.79

Displaying genes 3541 – 3550 of 10391 in total

Metabolites

48 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm00004573,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dioneC19H24O4Chemical structure of 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dioneNot available
Average316.3915Da
Monoisotopic316.1674593Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001429decanoateC10H19O2Chemical structure of decanoateNot available
Average171.2567Da
Monoisotopic171.138504852Da
BASm0001691hydrogenselenideHSeChemical structure of hydrogenselenideNot available
Average79.98Da
Monoisotopic80.924896Da
BASm0001774tetradecanoateC14H27O2Chemical structure of tetradecanoateNot available
Average227.363Da
Monoisotopic227.2011051Da
BASm0001775(9Z)-octadecenoateC18H33O2Chemical structure of (9Z)-octadecenoateNot available
Average281.4534Da
Monoisotopic281.2480553Da
BASm0001842(5Z,8Z,11Z,14Z)-eicosatetraenoateC20H31O2Chemical structure of (5Z,8Z,11Z,14Z)-eicosatetraenoateNot available
Average303.467Da
Monoisotopic303.2329538Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–10 of 48 metabolites

Health Effects

Health ConditionRelationReference
GastroenteritisCausesPMC12502522
DiarrheaCausesPMC12502522
GastroenteritisCausesPMC5109407
Food poisoningCausesPMC5109407
SalmonellosisCausesPMC6516042
Acute gastroenteritisCausesPMC6516042
Intestinal inflammationCausesPMC6516042
Gallbladder empyemaCausesPMC10442058
Disseminated diseaseCausesPMC10442058
GastroenteritisCausesPMC10442058

Displaying health effects 1 – 10 of 22 in total