Escherichia coli strain MNCRE44

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain MNCRE44 is a Gram-negative, rod-shaped bacterium, characterized by its mobility and the presence of flagella. This strain is a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. MNCRE44 is notable for its complex habitat, being host-associated, and it exhibits a free-living biotic relationship. This strain can be found in a diverse array of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, birds like Gallus gallus and Meleagris gallopavo, as well as other vertebrates and invertebrates like Apis mellifera and Acanthamoeba castellanii. The presence of multiple hosts indicates a broad ecological niche and adaptability of MNCRE44. Clinically, E. coli MNCRE44 is associated with numerous health effects, particularly those affecting the urinary tract, gastrointestinal system, and central nervous system. Reported health issues include urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and more severe conditions such as hemolytic uremic syndrome (HUS) and septicemia. These associations highlight its pathogenic potential in humans and other animals, emphasizing the strain's significance in both public health and veterinary contexts. The ability of MNCRE44 to inhabit such a wide range of hosts and its various pathogenic traits illustrate the complex interplay between microbial life and its host organisms, underscoring the importance of monitoring this strain within ecological and clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain MNCRE44

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain MNCRE44
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain MNCRE44 plasmid pMNCRE44_2, complete

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

3 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
conjugal transfer relaxosome dna-binding protein tramSY51_RS26450Not AvailablePositive33053 - 3343614477.3
pas domain-containing proteinSY51_RS26455Not AvailablePositive33570 - 3424726487.2
conjugal transfer relaxosome protein traySY51_RS26460Not AvailablePositive34335 - 345629072.72
type iv conjugative transfer system pilin traaSY51_RS26465Not AvailablePositive34596 - 3495812843.4
type iv conjugative transfer system protein tralSY51_RS26470Not AvailablePositive34963 - 3527411890.6
type iv conjugative transfer system protein traeSY51_RS26475Not AvailablePositive35296 - 3586221225.6
type-f conjugative transfer system secretin trakSY51_RS26480Not AvailablePositive35849 - 3657725591.6
f-type conjugal transfer pilus assembly protein trabSY51_RS26485Not AvailablePositive36577 - 3802851060.4
conjugal transfer pilus-stabilizing protein trapSY51_RS26490Not AvailablePositive38018 - 3858421358.7
conjugal transfer protein trbdSY51_RS26495Not AvailablePositive38571 - 3888210894.2

Displaying genes 191 – 200 of 296 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total