Bifidobacterium breve strain BR3

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve strain BR3 is a Gram-positive, anaerobic bacterium characterized by its rod shape and a single replicon. This strain is found predominantly in the gastrointestinal tract, specifically within human breast milk and the gut microbiota of healthy newborns. Bifidobacterium breve is a significant component of the infant gut microbiota, playing a crucial role in the early stages of human development. As a nonsporulating organism, Bifidobacterium breve BR3 relies on a stable environment for growth and survival. Its presence in breast milk suggests that it may be transmitted from mother to infant, contributing to the establishment of a healthy gut microbiome in newborns. This bacterium thrives in anaerobic conditions, which are typical of the intestinal environment, allowing it to effectively colonize the intestines of infants. The ecological role of Bifidobacterium breve strain BR3 extends beyond mere colonization; it is involved in the maintenance of gut health and development of the immune system in infants. By being a dominant species in the gut microbiota of newborns, it may aid in digestion and protect against pathogenic bacteria, thereby contributing to the overall well-being of the host. Understanding the specific traits and habitats of Bifidobacterium breve BR3 can help inform future research on its potential benefits in infant nutrition and health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strainstrain BR3

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve strain BR3
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain BR3 chromosome, complete genome.

Gene Summary

Adenine Count

491489 bp

Thymine Count

499132 bp

Guanine Count

718128 bp

Cytosine Count

712366 bp

Genome Length

2421115 bp

Protein-coding Genes

2043 genes

Non-Coding Genes

132 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
kup/hak/kt family potassium transporterRY69_RS10205Not AvailablePositive2339595 - 234200688767.2
class ii glutamine amidotransferaseRY69_RS10210Not AvailablePositive2342290 - 234315031304.5
hd domain-containing proteinRY69_RS10215Not AvailableNegative2343280 - 234404428689.5
atp-binding cassette domain-containing proteinRY69_RS11800Not AvailableNegative2344405 - 234558941371.6
abc transporter permeaseRY69_RS10225Not AvailableNegative2345586 - 234704651374.9
is256 family transposaseRY69_RS10230Not AvailableNegative2347295 - 234857548210.8
sulfatase-like hydrolase/transferaseRY69_RS10235Not AvailableNegative2348698 - 234970838684.8
lcp family proteinRY69_RS10240Not AvailablePositive2349993 - 235139649990.6
atp-binding proteinRY69_RS10245Not AvailableNegative2351768 - 235300346483.7
gh25 family lysozymeRY69_RS10250Not AvailablePositive2353470 - 235543470314.9

Displaying genes 2111 – 2120 of 2175 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.