Bifidobacterium breve strain BR3

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve strain BR3 is a Gram-positive, anaerobic bacterium characterized by its rod shape and a single replicon. This strain is found predominantly in the gastrointestinal tract, specifically within human breast milk and the gut microbiota of healthy newborns. Bifidobacterium breve is a significant component of the infant gut microbiota, playing a crucial role in the early stages of human development. As a nonsporulating organism, Bifidobacterium breve BR3 relies on a stable environment for growth and survival. Its presence in breast milk suggests that it may be transmitted from mother to infant, contributing to the establishment of a healthy gut microbiome in newborns. This bacterium thrives in anaerobic conditions, which are typical of the intestinal environment, allowing it to effectively colonize the intestines of infants. The ecological role of Bifidobacterium breve strain BR3 extends beyond mere colonization; it is involved in the maintenance of gut health and development of the immune system in infants. By being a dominant species in the gut microbiota of newborns, it may aid in digestion and protect against pathogenic bacteria, thereby contributing to the overall well-being of the host. Understanding the specific traits and habitats of Bifidobacterium breve BR3 can help inform future research on its potential benefits in infant nutrition and health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strainstrain BR3

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve strain BR3
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain BR3 chromosome, complete genome.

Gene Summary

Adenine Count

491489 bp

Thymine Count

499132 bp

Guanine Count

718128 bp

Cytosine Count

712366 bp

Genome Length

2421115 bp

Protein-coding Genes

2043 genes

Non-Coding Genes

132 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
inorganic diphosphataseRY69_RS08355Not AvailablePositive1854707 - 185520118353.5
manganese efflux pump mntp family proteinRY69_RS08360Not AvailablePositive1855437 - 185601520829.9
hypothetical proteinRY69_RS08365Not AvailablePositive1856075 - 185677924752.1
winged helix-turn-helix transcriptional regulatorRY69_RS08370Not AvailablePositive1856952 - 185772227569.6
endonuclease iiiRY69_RS08375Not AvailablePositive1857747 - 185841524788.8
abc transporter substrate-binding proteinRY69_RS08380Not AvailablePositive1858450 - 185997955017.2
valine--trna ligaseRY69_RS08385Not AvailablePositive1860100 - 1862835102189.0
hypothetical proteinRY69_RS08390Not AvailableNegative1862868 - 186485367710.0
chorismate mutaseRY69_RS08395Not AvailableNegative1865000 - 186538914093.6
aminodeoxychorismate lyaseRY69_RS08400Not AvailableNegative1865429 - 186640334745.4

Displaying genes 1731 – 1740 of 2175 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.