Bifidobacterium breve strain BR3

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve strain BR3 is a Gram-positive, anaerobic bacterium predominantly found in the gastrointestinal tracts of infants, particularly within the microbiota of healthy newborns. This strain is notably present in human breast milk and the intestines of infants, indicating its vital role in early gut colonization and development. Bifidobacterium breve is recognized for its contributions to gut health, including potential benefits for digestion and immune function during infancy. The anaerobic nature of B. breve strain BR3 suggests that it thrives in low-oxygen environments, which is characteristic of the gut microbiota. This adaptation allows it to flourish in the intestines, where it may interact synergistically with other microbial species, contributing to a balanced microbiome that is essential for the proper metabolism and health of the host. Additionally, the presence of B. breve in human breast milk underscores its significance in maternal-infant health dynamics, as maternal nutrition and microbiota can influence the colonization patterns of beneficial microbes in newborns. Overall, Bifidobacterium breve strain BR3 exemplifies a key microbial inhabitant of the infant gut, with implications for early development and long-term health. Its role in shaping the gut microbiome during infancy highlights the importance of early microbial exposure in establishing a resilient and diverse microbiota, which may have lasting effects on health throughout life.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strainstrain BR3

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain BR3


Gene Summary

Adenine Count

491489 bp

Thymine Count

499132 bp

Guanine Count

718128 bp

Cytosine Count

712366 bp

Genome Length

2421115 bp

Protein-coding Genes

2043 genes

Non-Coding Genes

132 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+718923 - 718996Not Available
Hypothetical proteinRY69_RS03095Not Available+720702 - 72167636589.2
Putative adenine methyltransferaseRY69_RS03100Not Available+721731 - 7219949964.02
hypothetical proteinRY69_RS03105Not Available-722108 - 72296531898.7
Site-specific recombinaseRY69_RS03110Not Available-723052 - 72463559152.0
Putative recombinaseRY69_RS03115Not Available-724635 - 72630863934.4
hypothetical proteinRY69_RS03120Not Available-726318 - 7265398251.09
hypothetical proteinRY69_RS03125Not Available-726536 - 72694615690.9
EndolysinRY69_RS03130Not Available-727101 - 72787727891.9
Holin family proteinRY69_RS03135Not Available-727874 - 72831415632.3

Displaying genes 1 – 10 of 2175 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites