Francisella tularensis subsp. novicida strain DPG 3A-IS

Gram-negativeRodNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Thiotrichales

Family

Francisellaceae

Genus

Francisella

Description

Francisella tularensis subsp. novicida strain DPG 3A-IS is a Gram-negative, rod-shaped bacterium that exhibits a free-living biotic relationship and inhabits aquatic environments. This strain is classified as an aerobe, meaning it requires oxygen for growth, and it is mesophilic, thriving within moderate temperature ranges. The cell arrangement of strain DPG 3A-IS is characterized by singles, indicating that the bacterial cells do not typically form clusters or chains. Notably, this strain lacks mobility, despite possessing flagella, which suggests that the flagella may not be functional for motility in this context. Genetically, strain DPG 3A-IS contains two replicons and has a double-membrane structure, a characteristic feature of many Gram-negative bacteria. Its health implications are significant, as it is associated with tularemia, a disease that can affect both humans and animals. The understanding of F. tularensis subsp. novicida strain DPG 3A-IS emphasizes its ecological role in aquatic habitats and highlights its potential impact on health through the transmission of tularemia. Its free-living nature allows it to interact with various environmental factors, which may influence its pathogenicity and survival strategies in natural ecosystems. The data underscore the importance of monitoring this bacterium in aquatic environments to assess risks to public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderThiotrichales
FamilyFrancisellaceae
GenusFrancisella
SpeciesFrancisella tularensis
Strainsubsp. novicida strain DPG 3A-IS

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Francisella tularensis subsp. novicida strain DPG 3A-IS
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatAquatic
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Ixodida
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityAnimal; Human

Genome Summary

Francisella tularensis subsp. novicida strain DPG 3A-IS plasmid

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

46 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein-export chaperone secbCH70_RS00030Not AvailableNegative5540 - 598916900.9
rhodanese-like domain-containing proteinCH70_RS00035Not AvailableNegative6016 - 643815863.3
omph family outer membrane proteinCH70_RS00040Not AvailableNegative6574 - 711319420.0
signal peptide peptidase sppaCH70_RS00045Not AvailableNegative7203 - 812634101.9
(2fe-2s) ferredoxin domain-containing proteinCH70_RS00050Not AvailablePositive8200 - 855313436.3
alpha-keto acid decarboxylase family proteinCH70_RS00055Not AvailablePositive8653 - 1035062256.3
cation:proton antiporterCH70_RS00060Not AvailableNegative10360 - 1161046038.5
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase ribdCH70_RS00065Not AvailablePositive12001 - 1306839591.1
riboflavin synthaseCH70_RS00070Not AvailablePositive13061 - 1366622183.9
3,4-dihydroxy-2-butanone-4-phosphate synthaseCH70_RS00075Not AvailablePositive13659 - 1487044610.7

Displaying genes 51 – 60 of 2009 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
TularemiaCausesPMC5413113
TularemiaCausesPMC11740472
TularemiaCausesPMC2752818
TularemiaCausesPMC3479022
TularemiaCausesPMC5023276
TularemiaCausesPMC5493697
TularemiaCausesPMC6187632

Displaying health effects 1 – 7 of 7 in total