Escherichia coli strain 94-3024

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 94-3024 is a Gram-negative, facultative anaerobic bacterium exhibiting a rod shape and capable of mobility due to the presence of flagella. It typically arranges itself in pairs or as singles and thrives at an optimal temperature of 37°C, falling within the mesophilic temperature range. This strain is characterized by having two replicons and two membranes, suggesting a complex genetic and structural organization. E. coli strain 94-3024 is host-associated, with a diverse range of potential hosts, including Homo sapiens, various livestock (Bos taurus, Sus scrofa), and other vertebrates and invertebrates such as Acanthamoeba and Apis mellifera. Its biotic relationship is classified as free-living, indicating its ability to survive independently in various environments. This strain is notably associated with a wide array of health effects, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. It has been implicated in multiple diseases affecting both humans and animals, including colibacillosis, foodborne infections, and complications leading to pregnancy loss and neonatal mortality. The ecological role of E. coli strain 94-3024 highlights its significant impact on health across species, illustrating the interconnectedness of microbial pathogens and their hosts. Its ability to cause a range of diseases underscores the importance of monitoring this strain in clinical and environmental contexts, as it poses risks not only to human health but also to animal welfare and food safety.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 94-3024

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 94-3024
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 94-3024 plasmid pO104_H21, complete

Gene Summary

Adenine Count

41280 bp

Thymine Count

40305 bp

Guanine Count

37875 bp

Cytosine Count

41987 bp

Genome Length

161447 bp

Protein-coding Genes

168 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
xanthine dehydrogenase molybdenum-binding subunit xdhaHW43_RS19305Not AvailablePositive3909031 - 391132882609.9
xanthine dehydrogenase fad-binding subunit xdhbHW43_RS19310Not AvailablePositive3911339 - 391221731558.6
xanthine dehydrogenase iron sulfur-binding subunit xdhcHW43_RS19315Not AvailablePositive3912214 - 391269316937.7
sigma-54 interaction domain-containing proteinHW43_RS19320Not AvailableNegative3912733 - 391451166073.0
knotted carbamoyltransferase ygewHW43_RS19325Not AvailablePositive3914990 - 391617744041.7
diaminopropionate ammonia-lyaseHW43_RS19330Not AvailablePositive3916235 - 391743143330.1
ygey family selenium metabolism-linked hydrolaseHW43_RS19335Not AvailablePositive3917489 - 391870044806.4
d-phenylhydantoinaseHW43_RS19340Not AvailablePositive3918753 - 392013851046.2
carbamate kinaseHW43_RS19345Not AvailablePositive3920186 - 392111833072.9
selenium-dependent molybdenum cofactor biosynthesis protein yqebHW43_RS19350Not AvailableNegative3921159 - 392278457685.4

Displaying genes 3981 – 3990 of 4929 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total