Escherichia coli strain 94-3024

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 94-3024 is a Gram-negative, facultative anaerobic bacterium exhibiting a rod shape and capable of mobility due to the presence of flagella. It typically arranges itself in pairs or as singles and thrives at an optimal temperature of 37°C, falling within the mesophilic temperature range. This strain is characterized by having two replicons and two membranes, suggesting a complex genetic and structural organization. E. coli strain 94-3024 is host-associated, with a diverse range of potential hosts, including Homo sapiens, various livestock (Bos taurus, Sus scrofa), and other vertebrates and invertebrates such as Acanthamoeba and Apis mellifera. Its biotic relationship is classified as free-living, indicating its ability to survive independently in various environments. This strain is notably associated with a wide array of health effects, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. It has been implicated in multiple diseases affecting both humans and animals, including colibacillosis, foodborne infections, and complications leading to pregnancy loss and neonatal mortality. The ecological role of E. coli strain 94-3024 highlights its significant impact on health across species, illustrating the interconnectedness of microbial pathogens and their hosts. Its ability to cause a range of diseases underscores the importance of monitoring this strain in clinical and environmental contexts, as it poses risks not only to human health but also to animal welfare and food safety.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 94-3024

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 94-3024
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 94-3024 plasmid pO104_H21, complete

Gene Summary

Adenine Count

41280 bp

Thymine Count

40305 bp

Guanine Count

37875 bp

Cytosine Count

41987 bp

Genome Length

161447 bp

Protein-coding Genes

168 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sorbitol-6-phosphate dehydrogenaseHW43_RS18285Not AvailablePositive3699945 - 370072427829.5
transcriptional regulator gutmHW43_RS18290Not AvailablePositive3700829 - 370118812954.0
glucitol operon dna-binding transcriptional repressor srlrHW43_RS18295Not AvailablePositive3701255 - 370202828237.8
arabinose-5-phosphate isomerase gutqHW43_RS18300Not AvailablePositive3702021 - 370298633989.5
nitric oxide reductase transcriptional regulator norrHW43_RS18305Not AvailableNegative3702983 - 370449755176.6
anaerobic nitric oxide reductase flavorubredoxinHW43_RS18310Not AvailablePositive3704684 - 370612354280.1
nadh:flavorubredoxin reductase norwHW43_RS18315Not AvailablePositive3706120 - 370725341388.2
carbamoyltransferase hypfHW43_RS18320Not AvailableNegative3707479 - 370973181904.4
electron transport protein hydnHW43_RS18325Not AvailableNegative3709884 - 371041119027.2
dna-binding transcriptional regulator ascgHW43_RS18330Not AvailableNegative3710560 - 371157036801.3

Displaying genes 3781 – 3790 of 4929 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total