Escherichia coli strain 94-3024

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain 94-3024 is a Gram-negative, facultative anaerobic bacterium exhibiting a rod shape and capable of mobility due to the presence of flagella. It typically arranges itself in pairs or as singles and thrives at an optimal temperature of 37°C, falling within the mesophilic temperature range. This strain is characterized by having two replicons and two membranes, suggesting a complex genetic and structural organization. E. coli strain 94-3024 is host-associated, with a diverse range of potential hosts, including Homo sapiens, various livestock (Bos taurus, Sus scrofa), and other vertebrates and invertebrates such as Acanthamoeba and Apis mellifera. Its biotic relationship is classified as free-living, indicating its ability to survive independently in various environments. This strain is notably associated with a wide array of health effects, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. It has been implicated in multiple diseases affecting both humans and animals, including colibacillosis, foodborne infections, and complications leading to pregnancy loss and neonatal mortality. The ecological role of E. coli strain 94-3024 highlights its significant impact on health across species, illustrating the interconnectedness of microbial pathogens and their hosts. Its ability to cause a range of diseases underscores the importance of monitoring this strain in clinical and environmental contexts, as it poses risks not only to human health but also to animal welfare and food safety.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain 94-3024

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain 94-3024
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 94-3024 plasmid pO104_H21, complete

Gene Summary

Adenine Count

41280 bp

Thymine Count

40305 bp

Guanine Count

37875 bp

Cytosine Count

41987 bp

Genome Length

161447 bp

Protein-coding Genes

168 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fluoride efflux transporter crcbHW43_RS07000Not AvailableNegative1440423 - 144080613766.1
deaminated glutathione amidaseHW43_RS07005Not AvailablePositive1440899 - 144168728683.0
twin-arginine translocase subunit tateHW43_RS07010Not AvailablePositive1441816 - 14420197024.71
lipoyl synthaseHW43_RS07015Not AvailableNegative1442120 - 144308536073.8
ybef family transcriptional regulatorHW43_RS07020Not AvailableNegative1443294 - 144424735904.4
lipoyl(octanoyl) transferase lipbHW43_RS07030Not AvailableNegative1444506 - 144514723864.9
duf493 family protein ybedHW43_RS07035Not AvailableNegative1445248 - 14455119827.92
d-alanyl-d-alanine carboxypeptidase dacaHW43_RS07040Not AvailableNegative1445622 - 144683344446.5
endolytic peptidoglycan transglycosylase rlpaHW43_RS07045Not AvailableNegative1446972 - 144806037502.0
peptidoglycan glycosyltransferase mrdbHW43_RS07050Not AvailableNegative1448071 - 144918340478.6

Displaying genes 1781 – 1790 of 4929 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total