Streptococcus oralis strain DD25

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus oralis strain DD25 is a Gram-positive, cocci-shaped bacterium characterized by its arrangement in pairs and chains. It is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. This strain is non-motile and does not possess flagella, which is typical for many streptococci. The habitat of S. oralis DD25 is primarily host-associated, with Homo sapiens identified as its main host. This bacterium is recognized for its pathogenic potential, being associated with several serious health conditions, including endocarditis, peritonitis, meningitis, infective endocarditis, and other invasive diseases. Its pathogenicity is particularly significant in human hosts, highlighting its role in opportunistic infections. S. oralis DD25 is mesophilic, thriving in moderate temperature ranges, and contains a single replicon, which is common among bacterial species. The strain's presence in the human microbiome suggests a complex biotic relationship, as it can be both free-living and pathogenic depending on the context. The ecological insight from this data indicates that while S. oralis can be a part of the normal microbiota, its ability to cause serious infections underscores the importance of maintaining a balanced microbial ecosystem in humans. Disruptions in this balance may lead to the opportunistic emergence of pathogens like S. oralis DD25, which can result in significant health challenges. Accessions for this strain are recorded under NZ_CM003838.1, providing a resource for further research and characterization.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus oralis
Strainstrain DD25

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus oralis strain DD25
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementPairs - Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus oralis strain DD25


Gene Summary

Adenine Count

1605 bp

Thymine Count

1796 bp

Guanine Count

850 bp

Cytosine Count

1230 bp

Genome Length

5481 bp

Protein-coding Genes

5 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinSORDD25_RS00015Not AvailableNegative623 - 227259024.6
hypothetical proteinSORDD25_RS09315Not AvailableNegative2315 - 24554769.09
hypothetical proteinSORDD25_RS00020Not AvailableNegative2518 - 295216822.2
hypothetical proteinSORDD25_RS00025Not AvailableNegative2952 - 324510685.9
protein repSORDD25_RS00030O52776Negative3825 - 479337867.7

Displaying genes 1 – 5 of 5 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

25 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002002glyoxylateC2HO3Chemical structure of glyoxylateNot available
Average73.0275Da
Monoisotopic72.9925689Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da
BASm00033514-methyl-5-(2-phosphooxyethyl)-thiazoleC6H8NO4PSChemical structure of 4-methyl-5-(2-phosphooxyethyl)-thiazoleNot available
Average221.17Da
Monoisotopic220.9922631Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da

Displaying 1–10 of 25 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6849159
Infective endocarditisCausesPMC6849159
Invasive diseaseCausesPMC9328907
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055

Displaying health effects 1 – 5 of 5 in total