Prevotella intermedia strain OMA14

Prevotella intermedia strain OMA14 is a Gram-negative, anaerobic rod-shaped bacterium predominantly found in various habitats within the human body, including the gingival sulci, oral cavity, gut, subgingival and supragingival dental biofilms, subgingival plaque, and the urogenital tract. This strain possesses flagella, which may facilitate its motility within these environments. Notably, Prevotella intermedia is associated with several health concerns. It is implicated in a range of conditions such as periodontal disease, dental caries, and various forms of periodontal inflammation, including periapical periodontitis and periodontal abscesses. Furthermore, it has been linked to more severe health issues, including intracranial infections and noma, indicating its pathogenic potential in humans. Prevotella intermedia strain OMA14 has two replicons, which may contribute to its genetic diversity and adaptability. The presence of this bacterium in both the oral cavity and the urogenital tract underscores its versatility and ability to thrive in different niches within the human microbiome. Ecologically, the association of Prevotella intermedia with periodontal disease highlights the importance of maintaining oral health to prevent the progression of infections that can have systemic implications. Its role in dental biofilms emphasizes the complex interactions between oral microbiota and host health, as well as the need for targeted strategies in managing oral diseases linked to this and similar pathogenic bacteria.