Mycobacterium avium subsp. hominissuis TH135

Mycobacterium avium subsp. hominissuis TH135 is a gram-positive, rod-shaped bacterium that is classified as a microaerophile, requiring low levels of oxygen for growth. This organism is a chemoorganotroph, meaning it derives its energy from organic compounds. M. avium subsp. hominissuis TH135 is host-associated, indicating a relationship with its host, although it is also described as free-living. This bacterium has a unique cellular structure, characterized by a single membrane and two replicons, which are features that may influence its genetics and adaptability. The optimal growth temperature for M. avium subsp. hominissuis TH135 is 37°C, falling within the mesophilic temperature range, indicating its preference for moderate temperatures typically found in warm-blooded hosts. M. avium subsp. hominissuis TH135 is non-motile; however, it possesses flagella, which may play a role in its interaction with the environment, despite its lack of mobility. This organism is associated with various hosts, particularly in contexts where it may lead to opportunistic infections in immunocompromised individuals. The ecological insight into M. avium subsp. hominissuis TH135 lies in its dual lifestyle as both a free-living and host-associated organism. This versatility may contribute to its persistence in diverse environments, allowing it to exploit organic matter while also establishing relationships with hosts, potentially leading to disease in susceptible populations. Accessions for this bacterium include NZ_AP012555.1 and NZ_AP012556.1, which provide genomic information for further study.