Streptococcus salivarius strain MIT 14-1770-C1

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus salivarius strain MIT 14-1770-C1 is a Gram-positive, cocci-shaped bacterium that typically forms chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. It is non-motile and lacks flagella, indicating that it does not have the means for active movement. The strain is mesophilic, thriving within a moderate temperature range optimal for growth. S. salivarius MIT 14-1770-C1 is host-associated, predominantly found in humans (Homo sapiens). Its biotic relationship is categorized as free-living, indicating that while it resides in a host, it can exist independently in certain environments. Importantly, this strain has been implicated in several health issues, including bacteremia, pneumonia, endocarditis, peritonitis, and meningitis. These associations highlight its potential pathogenicity in human health. The strain has a single replicon, which is characteristic of many bacteria, allowing for efficient replication and maintenance of genetic information. Notably, S. salivarius MIT 14-1770-C1 is nonsporulating, indicating that it does not form spores as a survival mechanism. The presence of S. salivarius in the human microbiome suggests its role in maintaining oral and systemic health, although its pathogenic potential underscores the importance of understanding its behavior in different environments and health contexts. This duality emphasizes the need for further research into its ecological interactions and potential therapeutic applications.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus salivarius
Strainstrain MIT 14-1770-C1

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus salivarius strain MIT 14-1770-C1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus salivarius strain MIT 14-1770-C1

Gene Summary

Adenine Count

711449 bp

Thymine Count

717895 bp

Guanine Count

468427 bp

Cytosine Count

457959 bp

Genome Length

2355730 bp

Protein-coding Genes

2048 genes

Non-Coding Genes

112 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
peptidase c39CQA85_04885Not AvailableNegative1018888 - 102096679559.2
salivaricin 9 biosynthesis lanthionine synthetase sivmCQA85_04890Not AvailableNegative1020983 - 1023766107650.0
type a2 lantipeptideCQA85_04895Not AvailableNegative1023933 - 10241036050.3
dna-binding response regulatorCQA85_04900Not AvailablePositive1024301 - 102499926453.3
two-component sensor histidine kinaseCQA85_04905Not AvailablePositive1025011 - 102637852438.7
dna-binding response regulatorCQA85_04925Not AvailableNegative1028379 - 102898423161.0
hypothetical proteinCQA85_04930Not AvailableNegative1028965 - 103052761140.9
abc transporter permeaseCQA85_04935Not AvailableNegative1030567 - 103247471915.9
bacitracin abc transporter atp-binding proteinCQA85_04940Not AvailableNegative1032476 - 103321327685.3
lantibiotic abc transporter atp-binding proteinCQA85_04945Not AvailableNegative1033210 - 103388725665.9

Displaying genes 951 – 960 of 2160 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC11536889
BacteremiaCausesPMC11536889
EndocarditisCausesPMC11536889
MeningitisCausesPMC11536889
PeritonitisCausesPMC9615012

Displaying health effects 1 – 5 of 5 in total