Streptococcus salivarius strain MIT 14-1770-C1

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus salivarius strain MIT 14-1770-C1 is a Gram-positive, cocci-shaped bacterium that typically forms chains or pairs. This strain is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. It is non-motile and lacks flagella, indicating that it does not have the means for active movement. The strain is mesophilic, thriving within a moderate temperature range optimal for growth. S. salivarius MIT 14-1770-C1 is host-associated, predominantly found in humans (Homo sapiens). Its biotic relationship is categorized as free-living, indicating that while it resides in a host, it can exist independently in certain environments. Importantly, this strain has been implicated in several health issues, including bacteremia, pneumonia, endocarditis, peritonitis, and meningitis. These associations highlight its potential pathogenicity in human health. The strain has a single replicon, which is characteristic of many bacteria, allowing for efficient replication and maintenance of genetic information. Notably, S. salivarius MIT 14-1770-C1 is nonsporulating, indicating that it does not form spores as a survival mechanism. The presence of S. salivarius in the human microbiome suggests its role in maintaining oral and systemic health, although its pathogenic potential underscores the importance of understanding its behavior in different environments and health contexts. This duality emphasizes the need for further research into its ecological interactions and potential therapeutic applications.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus salivarius
Strainstrain MIT 14-1770-C1

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus salivarius strain MIT 14-1770-C1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus salivarius strain MIT 14-1770-C1


Gene Summary

Adenine Count

711449 bp

Thymine Count

717895 bp

Guanine Count

468427 bp

Cytosine Count

457959 bp

Genome Length

2355730 bp

Protein-coding Genes

2048 genes

Non-Coding Genes

112 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
branched-chain amino acid abc transporter permeaseCQA85_01905Not AvailableNegative374508 - 37537730735.9
peptide abc transporter substrate-binding proteinCQA85_01910Not AvailableNegative375387 - 37638835614.9
duf4649 domain-containing proteinCQA85_01915Not AvailableNegative376525 - 3767468545.07
pyruvate kinaseCQA85_01925Not AvailableNegative377518 - 37902054474.2
6-phosphofructokinaseCQA85_01930Not AvailableNegative379091 - 38011035705.4
dna polymerase iii subunit alphaCQA85_01935Not AvailableNegative380203 - 383313118387.0
3-isopropylmalate dehydratase small subunitCQA85_01940Not AvailableNegative383528 - 38411822524.5
3-isopropylmalate dehydratase large subunitCQA85_01945Not AvailableNegative384130 - 38552150881.5
duf1294 domain-containing proteinCQA85_01950Not AvailableNegative385552 - 38583310688.8
3-isopropylmalate dehydrogenaseCQA85_01955Not AvailableNegative385838 - 38687537126.7

Displaying genes 381 – 390 of 2160 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC11536889
BacteremiaCausesPMC11536889
EndocarditisCausesPMC11536889
MeningitisCausesPMC11536889
PeritonitisCausesPMC9615012

Displaying health effects 1 – 5 of 5 in total