Escherichia coli strain KCJK3945

Escherichia coli strain KCJK3945 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, indicating its ability to grow in both aerobic and anaerobic conditions. This strain typically exists in pairs or singles and demonstrates mobility due to the presence of flagella. It is mesophilic, with an optimal growth temperature of 37°C. KCJK3945 is host-associated and exhibits a diverse range of biotic relationships, being free-living and associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and several other vertebrates and invertebrates, such as Apis mellifera (honeybees) and Solanum lycopersicum (tomatoes). This broad host range highlights the ecological versatility of the strain. The strain is known for its significant health effects in humans, where it is linked to numerous conditions such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and more severe complications like hemolytic uremic syndrome (HUS) and septicemia. Additionally, it can cause foodborne infections and contribute to conditions such as renal failure and colorectal cancer. The pathogenicity of E. coli strain KCJK3945 in humans underscores its potential public health impact, particularly in the context of food safety and infection control. Understanding its diverse host interactions and pathogenic mechanisms is crucial for developing strategies to mitigate the risks associated with its infections.