Klebsiella pneumoniae strain WBB417

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain WBB417 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is a chemoheterotroph, deriving energy from organic compounds, and exhibits a diverse range of biotic relationships, being free-living but also associated with multiple hosts including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and plants. The organism displays a unique cell arrangement, typically found in chains, pairs, or singles, and possesses flagella, contributing to its mobility. It has a mesophilic temperature range with an optimal growth temperature of 37°C, which corresponds to the normal human body temperature, facilitating its pathogenicity in human hosts. Klebsiella pneumoniae strain WBB417 is associated with numerous health effects, including bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. These infections often occur in both immunocompromised and healthy individuals, highlighting the strain's pathogenic potential. The presence of this bacterium in various animal species and its significant role in human disease underscores its ecological versatility and importance in microbiological research and clinical settings. Further understanding of its interactions within different hosts could provide insights into its pathogenic mechanisms and potential strategies for infection control.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain WBB417

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain WBB417
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain WBB417

Gene Summary

Adenine Count

1234990 bp

Thymine Count

1227345 bp

Guanine Count

1644154 bp

Cytosine Count

1642006 bp

Genome Length

5749690 bp

Protein-coding Genes

5363 genes

Non-Coding Genes

291 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
mfs transporter tsgaBVX91_21930Not AvailableNegative4351866 - 435305343398.3
peptidylprolyl isomerase aBVX91_21935Not AvailablePositive4353330 - 435389920390.4
duf2559 domain-containing proteinBVX91_21940Not AvailablePositive4354006 - 43541736501.81
cell filamentation protein ficBVX91_21945Not AvailablePositive4354163 - 435476522862.3
aminodeoxychorismate synthase component 2BVX91_21950Not AvailablePositive4354798 - 435536120572.7
aspartate aminotransferase family proteinBVX91_21955Not AvailablePositive4355452 - 435667243614.3
hypothetical proteinBVX91_21960Not AvailableNegative4356662 - 435874078614.7
camp-activated global transcriptional regulator crpBVX91_21965Not AvailableNegative4358792 - 435942423657.9
hypothetical proteinBVX91_21970Not AvailableNegative4359583 - 43597717041.39
hypothetical proteinBVX91_21975Not AvailablePositive4359731 - 436013514543.6

Displaying genes 4361 – 4370 of 5654 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1247 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1247 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total