Cutibacterium acnes strain P15-089

Cutibacterium acnes strain P15-089 is a Gram-positive, anaerobic, rod-shaped bacterium associated with human hosts, specifically Homo sapiens. This strain is non-motile and possesses flagella, which is atypical for many bacteria within the Cutibacterium genus. It has an optimal growth temperature of 37°C, placing it in the mesophilic temperature range. C. acnes strain P15-089 is known to be free-living and does not form spores. Notably, this strain has two replicons and a single membrane. It has been implicated in several health conditions, including acute bacterial meningitis, thoracic actinomycosis, and common acne. Furthermore, it has been associated with more severe health issues such as epithelial ovarian cancer and infectious complications following vertebroplasty or kyphoplasty procedures. The presence of C. acnes in various medical conditions suggests its significant role in human health, particularly regarding skin-related disorders and potential systemic infections. This strain exemplifies the complex interactions that bacteria can have within their host, indicating the need for further investigation into its pathogenic potential and ecological roles within the human microbiome. Understanding the implications of C. acnes in both health and disease can provide insights into the management of infections and the development of targeted treatments.