Faecalibacterium prausnitzii strain CNCM I 4644

Faecalibacterium prausnitzii strain CNCM I 4644 is a Gram-positive, non-motile, rod-shaped bacterium that functions as a chemoheterotroph, deriving its energy from organic compounds. This strain is anaerobic, meaning it thrives in environments devoid of oxygen, which is consistent with its habitat found in multiple sources, including the intestines of various hosts. Notably, it has been identified in Homo sapiens, Gallus gallus (domestic chickens), Metazoa, Aves, and primates like Macaca mulatta and Macaca fascicularis. Faecalibacterium prausnitzii strain CNCM I 4644 exhibits optimal growth at 37°C, placing it within the mesophilic temperature range. It possesses a single replicon and does not form spores, which may influence its ecological niche and adaptability in the gut microbiome. This strain is significant in microbial ecology due to its role in gut health. It is known for its anti-inflammatory properties and potential to contribute to the maintenance of gut barrier integrity. The presence of Faecalibacterium prausnitzii is often associated with a healthy gut microbiota, and its reduced levels have been linked to inflammatory bowel diseases. Therefore, understanding the characteristics of strain CNCM I 4644 contributes to our knowledge of its ecological role and potential therapeutic applications.