Faecalibacterium prausnitzii strain CNCM I 4575

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Oscillospiraceae

Genus

Faecalibacterium

Description

Faecalibacterium prausnitzii strain CNCM I 4575 is a Gram-positive, non-sporulating anaerobic bacterium characterized by its rod shape and lack of mobility. This strain is a chemoheterotroph, deriving its energy from organic compounds, which is typical for many gut-associated microorganisms. It thrives optimally at 37°C, placing it within the mesophilic temperature range. This strain has been identified in multiple habitats, particularly within the gastrointestinal tracts of various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several species of primates, such as Macaca mulatta and Macaca fascicularis. The presence of this bacterium across diverse Metazoa and Aves highlights its ecological significance and adaptability within different digestive environments. Faecalibacterium prausnitzii is notable for its role in gut health, often associated with anti-inflammatory properties and a potential protective effect against various gastrointestinal disorders. Its non-motility and anaerobic nature suggest a specialized niche within the gut microbiota, where it likely interacts with other microbial inhabitants and contributes to the maintenance of a balanced intestinal ecosystem. Overall, the ecological presence of Faecalibacterium prausnitzii strain CNCM I 4575 underscores its importance in the microbiome, particularly in relation to human health and disease prevention. The specific energy source and habitat preferences of this strain reflect its adaptive strategies and functional contributions to its hosts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyOscillospiraceae
GenusFaecalibacterium
SpeciesFaecalibacterium prausnitzii
Strainstrain CNCM I 4575

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Faecalibacterium prausnitzii strain CNCM I 4575
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Faecalibacterium prausnitzii strain CNCM I 4575


Gene Summary

Adenine Count

638413 bp

Thymine Count

638598 bp

Guanine Count

865384 bp

Cytosine Count

863857 bp

Genome Length

3006602 bp

Protein-coding Genes

2670 genes

Non-Coding Genes

165 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Dna polymeraseCGS58_06730Not AvailableNegative1426948 - 142751421307.7
phosphate acetyltransferaseCGS58_06735Not AvailablePositive1427702 - 142872735748.2
Putative dna polymerase iiiCGS58_06745Not AvailablePositive1429197 - 143107767833.7
nucleoid-associated protein, ybab/ebfc familyCGS58_06750Not AvailablePositive1431098 - 143143611993.5
recombination protein recrCGS58_06755Not AvailablePositive1431456 - 143205521774.4
Ssra-binding proteinCGS58_06760Not AvailablePositive1432166 - 143264818280.2
Tmrna,resume;Not AvailableNot AvailablePositive1432714 - 1433062Not Available
Hypothetical proteinCGS58_06770Not AvailablePositive1433304 - 143364212750.8
Hypothetical proteinCGS58_06775Not AvailablePositive1433790 - 14340058052.54
Hypothetical proteinCGS58_06780Not AvailablePositive1434019 - 143432711853.1

Displaying genes 1 – 10 of 2835 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

135 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da

Displaying 1–10 of 135 metabolites

Health Effects

No health effects information available for this bacterium.