Faecalibacterium prausnitzii strain CNCM I 4546

Faecalibacterium prausnitzii strain CNCM I 4546 is a Gram-positive, non-motile, rod-shaped bacterium that thrives in anaerobic environments. This strain is a chemoheterotroph, meaning it derives its energy from organic compounds, which is typical for many gut microbiota. It is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for the warm conditions typically found in the intestines of various hosts. This strain has been identified in multiple habitats, indicating a versatile ecological presence. It has been associated with various hosts, including Homo sapiens (humans), Gallus gallus (domestic chickens), Metazoa (multicellular animals), Aves (birds), and primates such as Macaca mulatta and Macaca fascicularis. The presence of Faecalibacterium prausnitzii in these diverse organisms suggests its significant role in gut microbiota across different species. Notably, this strain does not form spores and has a single replicon, indicating a streamlined genetic structure which may contribute to its adaptability in various gut environments. The absence of mobility and flagella suggests that it relies on other means of colonization within the gut ecosystem. Ecologically, Faecalibacterium prausnitzii is recognized for its potential health benefits, particularly in maintaining gut health and modulating immune responses. The diverse host range and its anaerobic, stable nature underscore its importance in microbial communities and its potential role in the gut health of various vertebrate hosts.