Bifidobacterium breve strain N6D12 C1090

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve strain N6D12 C1090 is a Gram-positive, anaerobic bacterium characterized by its rod shape and the presence of flagella. This strain is notable for its habitat, primarily residing in human breast milk and the gastrointestinal tract, particularly within the gut microbiota of healthy newborns. It plays a significant role in the infant intestine, contributing to the development of a healthy gut microbiome during early life. Bifidobacterium breve is nonsporulating and possesses a single replicon, which is indicative of its cellular organization and replication mechanism. Its presence in human breast milk suggests a potential for beneficial effects on infant health, as breast milk is known to be a primary source of nutrients and microbial colonizers for newborns. The dominance of Bifidobacterium species, including B. breve, in the gut microbiota of infants highlights the importance of these bacteria in establishing a balanced microbial community that can influence immune development and metabolic processes. The ecological insight derived from the distribution of Bifidobacterium breve in breast milk and the infant gut underscores the critical role of maternal health and nutrition in shaping the early microbiota of infants. This relationship suggests that breastfeeding may provide essential microbial inoculation, which is crucial for the formation of a healthy gut ecosystem in newborns. Accessions for this strain are cataloged under NJOA00000000.1, facilitating further research into its properties and potential applications in probiotic development.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strainstrain N6D12 C1090

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve strain N6D12 C1090
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain N6D12 C1090, whole genome shotgun

Gene Summary

Adenine Count

466364 bp

Thymine Count

464456 bp

Guanine Count

661580 bp

Cytosine Count

664871 bp

Genome Length

2290315 bp

Protein-coding Genes

1896 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
peptidase m23CE164_01000Not AvailablePositive231889 - 23251222686.4
hypothetical proteinCE164_01005Not AvailableNegative232525 - 23421058879.8
isocitrate dehydrogenase (nadp(+))CE164_01010Not AvailableNegative234351 - 23557145492.9
guab3 family imp dehydrogenase-related proteinCE164_01015Not AvailablePositive235700 - 23682439476.1
hypothetical proteinCE164_01020Not AvailablePositive236970 - 23745818413.7
long-chain fatty acid--coa ligaseCE164_01025Not AvailablePositive237534 - 23961575344.2
peptide deformylaseCE164_01030Not AvailablePositive239622 - 24010718268.9
hypothetical proteinCE164_01035Not AvailablePositive240404 - 2405535820.21
30s ribosomal protein s2CE164_01040Not AvailablePositive240671 - 24139926386.4
ump kinaseCE164_01050Not AvailablePositive242590 - 24333026587.1

Displaying genes 191 – 200 of 1952 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.