Escherichia coli strain FC10225

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FC10225 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain is capable of mobility, facilitated by the presence of flagella, and it typically exists in pairs or singles. It thrives optimally at 37°C and falls within the mesophilic temperature range. The ecological niche of E. coli FC10225 is primarily host-associated, and it exhibits a free-living biotic relationship. It has a diverse range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other mammals, birds, and even some plant species such as Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This indicates a broad adaptability to different environments and hosts. E. coli FC10225 is associated with multiple health effects, particularly in humans, where it is implicated in numerous conditions such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and more severe outcomes like septicemia and hemolytic uremic syndrome (HUS). These pathogenic traits highlight the strain’s potential influence on both human health and animal welfare. The strain's ability to inhabit a range of hosts and its association with significant health issues underscore its ecological importance. Understanding the interactions between E. coli FC10225 and its various hosts can provide insights into transmission dynamics and the development of effective intervention strategies to mitigate its pathogenic impact.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FC10225

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FC10225
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FC10225 Scaffold99, whole genome shotgun

Gene Summary

Adenine Count

1359687 bp

Thymine Count

1356016 bp

Guanine Count

1384703 bp

Cytosine Count

1392968 bp

Genome Length

5493374 bp

Protein-coding Genes

5119 genes

Non-Coding Genes

427 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Head completion/stabilization proteinCDL37_09660Not AvailableNegative1845555 - 184606419088.9
Terminase endonuclease subunitCDL37_09665Not AvailableNegative1846164 - 184690727501.7
Major capsid protein precursorCDL37_09670Not AvailableNegative1846911 - 184798440229.7
Capsid-scaffolding proteinCDL37_09675Not AvailableNegative1848042 - 184889631447.2
GppCDL37_09680Not AvailablePositive1849070 - 185084266588.2
Phage-related capsid packaging proteinCDL37_09685Not AvailablePositive1850842 - 185187639125.8
hypothetical proteinCDL37_09690Not AvailableNegative1852228 - 185312433781.0
Hypothetical proteinCDL37_09695Not AvailableNegative1853451 - 18536547778.58
Hypothetical proteinCDL37_09700Not AvailableNegative1853654 - 185410617304.6
GpaCDL37_09705Not AvailableNegative1854106 - 185639186352.8

Displaying genes 161 – 170 of 5546 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total