Mediterraneibacter gnavus strain RJX1118 RJX1118_125

Gram-positiveCocciNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Mediterraneibacter

Description

Mediterraneibacter gnavus strain RJX1118 (accession NIHM00000000.1) is a Gram-positive, non-motile cocci that resides in the intestinal microflora of Homo sapiens. This bacterium is classified as a chemoheterotroph, deriving its energy from organic compounds in its anaerobic environment, which aligns with its habitat within the human gut. Optimal growth of M. gnavus RJX1118 occurs at 37°C, placing it within the mesophilic temperature range, conducive to human body conditions. This strain is notable for its single replicon structure and nonsporulating nature, indicating a stable genomic organization and a reliance on fermentation processes in the absence of oxygen. Research indicates that M. gnavus has potential health implications, particularly in relation to inflammatory bowel disease (IBD). Its pathogenicity in humans suggests a role in the dysbiosis often observed in individuals suffering from IBD, although the exact mechanisms remain to be elucidated. The presence of M. gnavus in the intestinal microbiome may provide insights into the complex interactions between gut flora and human health. Understanding its role could be crucial for developing therapeutic strategies aimed at restoring microbial balance and addressing conditions such as IBD. Overall, the characteristics of Mediterraneibacter gnavus strain RJX1118 highlight its significance in both microbial ecology and human health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusMediterraneibacter
SpeciesMediterraneibacter gnavus
Strainstrain RJX1118 RJX1118_125

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Mediterraneibacter gnavus strain RJX1118 RJX1118_125
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Mediterraneibacter gnavus strain RJX1118 RJX1118_125


Gene Summary

Adenine Count

901755 bp

Thymine Count

913373 bp

Guanine Count

677859 bp

Cytosine Count

689564 bp

Genome Length

3183499 bp

Protein-coding Genes

2901 genes

Non-Coding Genes

66 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
anthranilate phosphoribosyltransferaseCDL18_02725Not AvailableNegative574317 - 57534236538.9
anthranilate synthase component iCDL18_02735Not AvailableNegative575912 - 57737854544.8
type ii toxin-antitoxin system antitoxin, relb/dinj familyCDL18_02745Not AvailablePositive578261 - 57856610803.1
rele/pare family toxinCDL18_02750Not AvailablePositive578563 - 57889212641.0
dna-binding proteinCDL18_02755Not AvailableNegative579028 - 57988533035.7
hypothetical proteinCDL18_02760Not AvailableNegative579869 - 58015911328.4
23s rrna (uracil-5-)-methyltransferase rumaCDL18_02770Not AvailableNegative580473 - 58191554170.7
hdig domain-containing proteinCDL18_02775Not AvailableNegative581936 - 58287735707.4
trypsinCDL18_02780Not AvailableNegative582912 - 58420446556.4
endonuclease muts2CDL18_02785Not AvailablePositive584332 - 58670788413.1

Displaying genes 531 – 540 of 2967 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Inflammatory bowel disease (ibd)CausesPMC12034673

Displaying health effects 1 – 1 of 1 in total