Porphyromonas gingivalis strain KCOM 2797 JS2_44

Porphyromonas gingivalis strain KCOM 2797 JS2_44 is a Gram-negative, anaerobic bacterium characterized by its rod shape and absence of mobility, indicating a non-motile lifestyle. This strain is associated with a host environment, specifically found in humans (Homo sapiens) and domestic dogs (Canis lupus familiaris). It exhibits mesophilic growth, with an optimal temperature of 37°C, which aligns with the body temperature of its hosts. Notably, Porphyromonas gingivalis is implicated in various oral health issues, including periodontitis and dysbiosis, affecting both human and canine populations. Its pathogenicity in humans is particularly concerning, as it is linked to chronic periodontitis and other periodontal diseases, which can have broader health implications, including potential associations with colorectal cancer (CRC). The bacterium's ability to thrive in anaerobic conditions allows it to flourish in the subgingival space of the oral cavity, a niche often deprived of oxygen. This strain features a single replicon and possesses two membranes, typical of Gram-negative bacteria, which may contribute to its survival and pathogenicity in host environments. The absence of sporulation suggests that it relies on other mechanisms for persistence and transmission within its ecological niche. In summary, Porphyromonas gingivalis strain KCOM 2797 JS2_44 exemplifies the complex interactions between oral microbiota and host health, highlighting the importance of understanding such bacteria in the context of periodontal diseases and their broader implications in systemic health.