Escherichia coli strain CVAST0582

Escherichia coli strain CVAST0582 is a Gram-negative, rod-shaped bacterium that exhibits mobility and possesses flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. The strain is mesophilic, with an optimal growth temperature of 37°C, which is typical for many pathogenic bacteria associated with warm-blooded hosts. This strain is primarily host-associated, demonstrating a diverse range of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and numerous other mammals, birds, and invertebrates. Its free-living biotic relationship indicates that it can survive independently in various environments, although it is often associated with its hosts. CVAST0582 is associated with a wide array of health effects, particularly in humans, where it is implicated in urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions like neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's pathogenicity is significant, given its ability to cause various infections, including peritonitis, diarrhea, and even complications leading to renal failure. The broad host range and the diversity of health impacts suggest that E. coli strain CVAST0582 plays a complex role in both human health and animal health, highlighting its potential as a significant pathogen in the environment and within host populations. This underscores the importance of monitoring and understanding such strains, especially in the context of foodborne illnesses and zoonotic diseases.